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J-GLOBAL ID：200902208646516082   Reference number：06A0095551

DNA Sequencing and Transcriptional Analysis of the Kasugamycin Biosynthetic Gene Cluster from Streptomyces kasugaensis M338-M1

Streptomyces kasugaensis M338-M1のカスガマイシン生合成遺伝子クラスターのDNA配列と転写分析

Author (5)： IKENO Souichi (Showa Pharmaceutical Univ., Tokyo, JPN) ,  AOKI Daisuke (Showa Pharmaceutical Univ., Tokyo, JPN) ,  HAMADA Masa (Inst. Microbial Chemistry, Tokyo, JPN) ,  HORI Makoto (Showa Pharmaceutical Univ., Tokyo, JPN) ,  TSUCHIYA Kayoko S. (Showa Pharmaceutical Univ., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 59  Issue： 1  Page： 18-28  Publication year： Jan. 25, 2006 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antibiotic producing microorganism ,...
Semi thesaurus term： *Streptomyces ,...

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JST classification (2)： Antibiotic-producing microorganisms  (GX02000L) ,  Gene expression  (EC02040Q)

Substance index (1)： Kasugamycin

Reference (37)：

• UMEZAWA, H. Kasugamycin, a new antibiotic. Antimicrob Agents Chemother. 1965, 5, 753-757
• IKENO, S. Correlation between the presence of kac, kasugamycin acetyltransferase gene, and the productivity of kasugamycin in Strepromyces. Actinomycetologica. 1996, 10, 73-79
• IKENO, S. A 7.6kb DNA region from Streptomyces kasugaensis M338-M1 includes some genes responsible for kasugamycin biosynthesis. J Antibiot. 1998, 51, 341-352
• IKENO, S. kasT gene of Streptomyces kasugaensis M338-M1 encodes a DNA-binding protein which binds to intergenic region of kasU-kasJ in the kasugamycin biosynthesis gene cluster. J Antibiot. 2002, 55, 1053-1062
• IKENO, S. ABC transporter genes, kasKLM, responsible for self-resistance of a kasugamycin producer strain. J Antibiot. 2000, 53, 373-384

Terms in the title (7)： Streptomyces ,  カスガマイシン ,  生合成遺伝子 ,  クラスター ,  DNA配列 ,  転写 ,  分析