Art

J-GLOBAL ID：200902210337347491   Reference number：05A0510476

Meloxicam inhibits the growth of non-small cell lung cancer

メロキシカムによる非小細胞肺癌の増殖抑制効果

Author (4)： TSUBOUCHI YASUNORI (京都府医大 こう原病・リウマチ・アレルギー内科学部門 生体機能制御学) ,  KAWAHITO YUTAKA (京都府医大 こう原病・リウマチ・アレルギー内科学部門 生体機能制御学) ,  SANO HAJIME (兵庫医大 総合内科学 リウマチ・こう原病科) ,  YOSHIKAWA TOSHIKAZU (京都府医大 こう原病・リウマチ・アレルギー内科学部門 生体機能制御学)
Material： 炎症・再生  (Inflammation and Regeneration)
Volume： 25  Issue： 3  Page： 177-180  Publication year： May. 25, 2005 
JST Material Number： Y0899A  ISSN： 1346-8022  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： cyclooxygenase ,...
Semi thesaurus term： *non-small cell lung cancer

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JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： Meloxicam

Reference (13)：

• 1) Hida T, Leyton J, Makheja AN, Ben-av P, Hla T, Martinez A, Mulshine J, Malkani S, Chung P, Moody TW: Non-small cell lung cancer cyclooxygenase activity and proliferation are inhibited by non-steroidal antiinflammatory drugs. Anticancer Res, 18: 775-782, 1998.
• 2) Tsubouchi Y, Sano H, Kawahito Y, Mukai S, Yamada R, Kohno M, Inoue K, Hla T, Kondo M: Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor(PPAR)-γ agonists through induction of apoptosis. Biochem Biophys Res Commun, 270: 400-405, 2000.
• 3) Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature, 231: 232-237, 1971.
• 4) Avis IM, Jett M, Boule T, Vos MD, Moody T, Treston AM, Martinez A, Mulshine JL: Growth control of lung cancer by interruption of 5-Lipoxygenase-mediated growth factor signaling. J Clin Invest, 97: 806-813, 1996.
• 5) Vane JR, Mitchell JA, Appleton I, Tomlinson A, Bishop-Bailey D, Croxtall J, Willoughby DA: Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci USA, 91: 2046-2050, 1994.

Terms in the title (3)： メロキシカム ,  非小細胞肺癌 ,  増殖抑制効果