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J-GLOBAL ID：200902210419259035   Reference number：04A0645323

Synthesis and physical and physiological properties of 4′-thioRNA: application to post-modification of RNA aptamer toward NF-κB

4′-チオRNAの合成,並びに物理的及び生理学的性質:NF-κBに対するRNAアプタマーのポスト修飾への応用

Author (3)： HOSHIKA S (Hokkaido Univ., Sapporo, JPN) ,  MINAKAWA N (Hokkaido Univ., Sapporo, JPN) ,  MATSUDA A (Hokkaido Univ., Sapporo, JPN)
Material： Nucleic Acids Research  (Nucleic Acids Res)
Volume： 32  Issue： 13  Page： 3815-3825  Publication year： 2004 
JST Material Number： D0242C  ISSN： 0305-1048  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *functional polymer ,...
Semi thesaurus term： 4′-チオRNA

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JST classification (2)： Nucleic acids in general  (EB04010U) ,  Gene expression  (EC02040Q)

Substance index (15)： 1-[2-O-(tert-Butyldimethylsilyl)-3-O,5-O-[oxybis(dimethylsilanediyl)]-4-thio-β-D-ribo-pentofuranosyl]uracil ,  1-[2-O-(tert-Butyldimethylsilyl)-4-thio-β-D-ribo-pentofuranosyl]uracil ,  1-[2-O-(tert-Butyldimethylsilyl)-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]uracil ,  1-[2-O-(tert-Butyldimethylsilyl)-3-O-[dimethylamino(methoxy)phosphino]-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]uracil ,  1-[2-O-(tert-Butyldimethylsilyl)-3-O-(3-carboxypropanoyl)-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]uracil ,  N-Benzoyl-1-[2-O-(tert-butyldimethylsilyl)-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]cytosine ,  N-Benzoyl-1-[2-O-(tert-butyldimethylsilyl)-3-O-[dimethylamino(methoxy)phosphino]-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]cytosine ,  N-Benzoyl-1-[2-O-(tert-butyldimethylsilyl)-3-O-(3-carboxypropanoyl)-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]cytosine ,  9-[3-O,5-O-[Oxybis(dimethylsilanediyl)]-4-thio-β-D-ribo-pentofuranosyl]-9H-purine-6-amine ,  9-[2-O-(tert-Butyldimethylsilyl)-3-O,5-O-[oxybis(dimethylsilanediyl)]-4-thio-β-D-ribo-pentofuranosyl]-9H-purine-6-amine ,  N-Benzoyl-9-[2-O-(tert-butyldimethylsilyl)-3-O,5-O-[oxybis(dimethylsilanediyl)]-4-thio-β-D-ribo-pentofuranosyl]-9H-purine-6-amine ,  N-Benzoyl-9-[2-O-(tert-butyldimethylsilyl)-4-thio-β-D-ribo-pentofuranosyl]-9H-purine-6-amine ,  N-Benzoyl-9-[2-O-(tert-butyldimethylsilyl)-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]-9H-purine-6-amine ,  N-Benzoyl-9-[2-O-(tert-butyldimethylsilyl)-3-O-[diisopropylamino(methoxy)phosphino]-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-ribo-pentofuranosyl]-9H-purine-6-amine ,  N-(Dimethylaminomethylene)-9-(4-thio-β-D-ribo-pentofuranosyl)-9H-purine-2-amine

Terms in the title (8)： RNA ,  物理 ,  生理学 ,  性質 ,  NF-κB ,  RNAアプタマー ,  修飾 ,  応用