Art

J-GLOBAL ID：200902210516414134   Reference number：03A0666481

Effect of 5-fluorouracil and epidermal growth factor on cell growth and dihydropyrimidine dehydrogenase regulation in human uterine cervical carcinoma SKG-IIIb cells

細胞成長及びヒト子宮頚管癌腫SKG-IIIb細胞におけるジヒドロピリミジンデヒドロゲナーゼ調節への5-フルオロウラシル及び上皮成長因子の効果

Author (3)： KASHIMA N (Kyowa Hakko Kogyo Co., Ltd., Shizuoka) ,  UEDA M (Osaka Medical Coll., Osaka) ,  KANAZAWA J (Kyowa Hakko Kogyo Co., Ltd., Shizuoka)
Material： Cancer Science  (Cancer Sci)
Volume： 94  Issue： 9  Page： 821-825  Publication year： Sep. 30, 2003 
JST Material Number： F0633A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： ジヒドロピリミジンデヒドロゲナーゼ

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JST classification (2)： Experimental treatment for tumors  (GE02040Y) ,  Tumors(=neoplasms)of female genitalia and fetus  (GS04000K)

Substance index (2)： 1,4-Dihydropyrimidine ,  Fluorouracil

Reference (22)：

• UEKI, M. Individualization of patients for adjuvant chemotherapy after surgical treatment of cervical cancer. Br J Obstet Gynaecol. 1987, 94, 985-990
• UEDA, M. Growth inhibition and apoptotic cell death in uterine cervical carcinoma cells induced by 5-fluorouracil. Int J Cancer. 1997, 71, 668-674
• DAHER, GC. Metabolism of pyrimidine analogues and their nucleosides. Pharmacol Ther. 1990, 48, 189-222
• DIASIO, RB. Clinical pharmacology of 5fluorouracil. Clin Pharmacokinet. 1989, 16, 215-237
• ETIENNE, MC. Response to fluorouracil therapy in cancer patients : the role of tumoral dihydopyrimidine dehydrogenase activity. J Clin Oncol. 1995, 13, 1663-1670

Terms in the title (8)： 細胞成長 ,  ヒト ,  子宮頚管癌 ,  細胞 ,  ジヒドロピリミジンデヒドロゲナーゼ ,  調節 ,  5-フルオロウラシル ,  上皮成長因子