Art

J-GLOBAL ID：200902210582532229   Reference number：08A0027066

A Phase I Study of the Safety of the Nutritional Supplement, Active Hexose Correlated Compound, AHCC, in Healthy Volunteers

健常ボランティアにおける栄養強化剤,活性ヘキソース関連化合物,AHCC,の安全性の第一相試験

Author (6)： SPIERINGS Egilius L. H. (Medvadis Res. Corp., Massachusetts, USA) ,  SPIERINGS Egilius L. H. (Harvard Medical School, Massachusetts, USA) ,  FUJII Hajime (Amino Up Chemical Co. Ltd., Sapporo, JPN) ,  SUN Buxiang (Amino Up Chemical Co. Ltd., Sapporo, JPN) ,  WALSHE Thomas (Harvard Medical School, Massachusetts, USA) ,  WALSHE Thomas (Academic Res. Associates)
Material： Journal of Nutritional Science and Vitaminology  (Nutritional Science and Vitaminology)
Volume： 53  Issue： 6  Page： 536-539  Publication year： Dec. 2007 
JST Material Number： F0733A  ISSN： 0301-4800  CODEN： JNSVA5  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Lentinus edodes ,...
Semi thesaurus term： Food and Drug Administration ,...

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JST classification (2)： Vegetables and processed vegetable products  (FJ11020O) ,  Pharmacology in general  (GW01000B)

Reference (10)：

• 1) Kosuna K. 1993. The development and application of active hemicellulose compound (AHCC). BioIndustry 10: 555-558 (in Japanese).
• 2) Matsushita K, Kuramitsu Y, Ohiro Y, Obara M, Kobayashi M, Li YQ, Hosokawa M. 1998. Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anticancer Drugs 9: 343-350.
• 3) Sun B, Wakame K, Mukoda T, Toyoshima A, Kanazawa T, Kosuna K. 1997. Preventive effects of AHCC on carbon tetrachloride induced liver injury in mice. Nat Med 51: 310-315 (in Japanese).
• 4) Mukoda T, Sun B. 1998. AHCC protects against cytosine arabinoside induced alopecia in the newborn rat animal model. Fifty-Seventh Annual Meeting of the Japanese Cancer Association (in Japanese).
• 5) Matsui Y, Uhara J, Satoi S, Kaibori M, Yamada H, Kitade H, Imamura A, Takai S, Kawaguchi Y, Kwon A, Kamiyama Y. 2002. Improved prognosis of post-operative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study. J Hepatol 37: 78-86.

Terms in the title (6)： 健常ボランティア ,  栄養強化剤 ,  活性ヘキソース関連化合物 ,  AHCC ,  安全性 ,  第一相試験