Art

J-GLOBAL ID：200902210680410174   Reference number：04A0032990

Optimizing outcomes with antimicrobial therapy through pharmacodynamic profiling

薬力学的プロファイル化による抗菌薬療法の最適化の成果

Author (1)： NICOLAU D P (Hartford Hospital, CT, USA)
Material： Journal of Infection and Chemotherapy  (J Infect Chemother)
Volume： 9  Issue： 4  Page： 292-296  Publication year： Dec. 2003 
JST Material Number： L2852A  ISSN： 1341-321X  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *aminoglycoside antibiotics ,...
Semi thesaurus term： MIC(concentration) ,...

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JST classification (2)： Drugs acting on pathogenic organisms in general  (GW17010H) ,  Basic research of antibiotics acting on pathogenic organisms  (GX05020C)

Reference (33)：

• NICOLAU, DP. Optimizing antimicrobial therapy and emerging pathogens. Am J Man Care. 1998, 4, 10(Suppl 2, 525-530
• AMBROSE, PG. The use of Monte Carlo simulation to examine pharmacodynamic variance of drugs : fluoroquinolone pharmacodynamics against Streptococcus pneumoniae. Diagn Microbiol Infect Dis. 2000, 38, 151-157
• MONTGOMERY, MJ. Population pharmacokinetics and use of Monte Carlo simulation to evaluate currently recommended dosing regimens of ciprofloxacin in adult patients with cystic fibrosis. Antimicrob Agents Chemother. 2001, 45, 3468-3473
• NICOLAU, DP. Pharmacodynamic profiling of levofloxacin and gatifloxacin using Monte Carlo simulation for community-acquired isolates of Streptococcus pneumoniae. Am J Med. 2001, 111, Suppl 9A, 13S-18S
• DRUSANO, GL. Levofloxacin penetration into epithelial lining fluid as determined by population pharmacokinetic modeling and Monte Carlo simulation. Antimicrob Agents Chemother. 2002, 46, 586-589

Terms in the title (5)： 薬力学 ,  プロファイル ,  抗菌薬療法 ,  最適化 ,  成果