Art

J-GLOBAL ID：200902211053666704   Reference number：08A0545857

SYNTHESIS OF THE DIAZATRICYCLIC CORE OF MADANGAMINES VIA CYCLIC N,O-ACETALIZATION-BRIDGEHEAD REDUCTION

環状N,O-アセタール化-橋頭堡還元によるマダンアミン類(Madangamines)のジアザトリシクロコアの合成

Author (5)： YOSHIMURA Yuta (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  KUSANAGI Takahiko (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  KIBAYASHI Chihiro (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  YAMAZAKI Naoki (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  AOYAGI Sakae (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 75  Issue： 6  Page： 1329-1354  Publication year： Jun. 01, 2008 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Porifera ,  heterocyclic compound ,  acetalation ,  hydrogenolysis ,  total synthesis ,  annulation ,  organic compound ,  *alkaloid ,  *Heterocyclic Compounds, 3-Ring ,  cytotoxin ,  Xestospongia ,  invertebrate ,  antitumor drug ,  drug
Semi thesaurus term： cytotoxin ,  Xestospongia ,  cytotoxic agent

JST classification (2)： Other condensed derivatives of pyridine  (CF07097Y) ,  Cyclization reaction,ring-opening reaction  (CF02050I)

Substance index (3)： (1S,13R,14S)-14-(tert-Butyldimethylsilyloxy)-12,12-bis[(methoxymethoxy)methyl]-2-oxa-10-azatetracyclo[11.3.1.0^1,10.0^3,8]heptadecane-3,5,7-triene ,  2-[[(4S,5R,6S)-6-(tert-Butyldimethylsilyloxy)-4-(hydroxymethyl)-4-(methoxymethoxymethyl)-2-azabicyclo[3.3.1]nonane-2-yl]methyl]phenol ,  (1R,4S,8S,9S)-4-(Benzyloxymethyl)-2,6-diazatricyclo[6.2.2.0^4,9]dodecane-2,6-dicarboxylic acid 2-tert-butyl 6-benzyl ester

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Terms in the title (3)： 環状 ,  アセタール化 ,  還元