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J-GLOBAL ID：200902211458778100
Reference number：09A0070897
Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients: is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?
結腸癌患者の5-フルオロウラシルベースの化学療法の臨床転帰の予測 CpGアイランドメチル化形質は5-フルオロウラシル応答性亜群であるか?
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Author (3)：
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Material：
Volume：
13
Issue：
6
Page：
498-503
Publication year：
Dec. 2008
JST Material Number：
L3966A
ISSN：
1341-9625
Document type：
Article
Article type：
文献レビュー
Country of issue：
Germany, Federal Republic of (DEU)
Language：
ENGLISH (EN)
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Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Drug therapy(=pharmacotherapy)for tumors
, Clinical application of antitumor(=antineoplastic)drugs
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Substance index
Chemical Substance indexed to the Article.
Reference (62)：
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DANENBERG, PV. Effect of 5, 10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase : evidence for an ordered mechanism. Biochemistry. 1978, 17, 4018-4024
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RUSTUM, YM. Biochemical and pharmacologic basis for potentiation of 5-fluorouracil action by leucovorin. NCI Monogr. 1987, 5, 165-170
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THIRION, P. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer : an updated meta-analysis. J Clin Oncol. 2004, 22, 3766-3775
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LONGLEY, DB. 5-Fluorouracil : mechanisms of action and clinical strategies. Nat Rev Cancer. 2003, 3, 330-338
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GRAZIANO, F. Prognostic molecular markers for planning adjuvant chemotherapy trials in Dukes' B colorectal cancer patients : how much evidence is enough?. Ann Oncol. 2003, 14, 1026-1038
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Terms in the title
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