Art
J-GLOBAL ID：200902211622882496   Reference number：08A1107517

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes

薬物誘導のりん脂質症はリソソーム酵素のマンノンース6-りん酸受容体仲介標的化の阻止により起される
Author (7)：
IKEDA Kazuhiko

About IKEDA Kazuhiko

(Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...)

About Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...

, 
IKEDA Kazuhiko

About IKEDA Kazuhiko

(Drug Safety Res. Labs., Astellas Pharma Inc., 1-6 Kashima 2-chome, Yodogawa-Ku, Osaka 532-8514, JPN)

About Drug Safety Res. Labs., Astellas Pharma Inc., 1-6 Kashima 2-chome, Yodogawa-Ku, Osaka 532-8514, JPN

, 
HIRAYAMA Masahiro

About HIRAYAMA Masahiro

(Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...)

About Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...

, 
HIROTA Yuko

About HIROTA Yuko

(Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...)

About Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...

, 
ASA Erika

About ASA Erika

(Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...)

About Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...

, 
SEKI Jiro

About SEKI Jiro

(Drug Safety Res. Labs., Astellas Pharma Inc., 1-6 Kashima 2-chome, Yodogawa-Ku, Osaka 532-8514, JPN)

About Drug Safety Res. Labs., Astellas Pharma Inc., 1-6 Kashima 2-chome, Yodogawa-Ku, Osaka 532-8514, JPN

, 
TANAKA Yoshitaka

About TANAKA Yoshitaka

(Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...)

About Div. of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu Univ., 3-1-1 Maidashi ...


Material：
Biochemical and Biophysical Research Communications  (BBRC)

About Biochemical and Biophysical Research Communications


Volume： 377  Issue： 1  Page： 268-274  Publication year： Dec. 05, 2008 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
fibroblast

About fibroblast

, 
cultured cell

About cultured cell

, 
*amphiphilic

About amphiphilic

, 
*drug

About drug

, 
phospholipid

About phospholipid

, 
*liver cirrhosis

About liver cirrhosis

, 
*metabolic disease

About metabolic disease

, 
*lysosome

About lysosome

, 
endosome

About endosome

, 
membrane transport receptor

About membrane transport receptor

, 
IGF receptor

About IGF receptor

, 
subcellular distribution

About subcellular distribution

, 
secretion(physiology)

About secretion(physiology)

, 
*enzyme

About enzyme

, 
storage and accumulation

About storage and accumulation

, 
medium(culture)

About medium(culture)

, 
screening(inspection)

About screening(inspection)


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
Receptor, IGF Type 2

About Receptor, IGF Type 2

, 
NRK cell

About NRK cell

, 
mannose 6-phosphate receptor

About mannose 6-phosphate receptor

, 
*Phospholipidosis

About Phospholipidosis


JST classification (4)：
JST classification
Category name(code) classified by JST.
Basic medicine on digestive system 
(GH01020E)

About Basic medicine on digestive system

,  Metabolic diseases,nutritional diseases in general. 
(GD05010J)

About Metabolic diseases,nutritional diseases in general.

,  Enzyme in general 
(EB09010D)

About Enzyme in general

,  Toxicity of organic compounds 
(GZ02030Y)

About Toxicity of organic compounds

Terms in the title (8)：
Terms in the title
Keywords automatically extracted from the title.
薬物

About 薬物

, 
誘導

About 誘導

, 
りん脂質症

About りん脂質症

, 
リソソーム酵素

About リソソーム酵素

, 
酸受容体

About 酸受容体

, 
仲介

About 仲介

, 
標的化

About 標的化

, 
阻止

About 阻止


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