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J-GLOBAL ID：200902212114308632   Reference number：06A0170743

Ameliorating Effect of Dimethylsulfoniopropionate on the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson’s Disease of Mice

マウスの1-メチル-4-フェニル-1,2,3,6-テトラヒドロピリジン-誘導パーキンソン病に対するジメチススルホニオプロピオナートの改善効果

Author (2)： NAKAJIMA Kenji (Koshien Univ., Hyogo, JPN) ,  MINEMATSU Masaharu (Kansai Univ. Welfare Sci., Osaka, JPN)
Material： Journal of Nutritional Science and Vitaminology  (Nutritional Science and Vitaminology)
Volume： 52  Issue： 1  Page： 70-74  Publication year： Feb. 2006 
JST Material Number： F0733A  ISSN： 0301-4800  CODEN： JNSVA5  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Parkinson's disease ,...

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JST classification (1)： Central nervous system  (EJ12030F)

Substance index (4)： Dimethylsulfoniopropionate ,  Dopamine ,  Norepinephrine ,  MPTP

Reference (25)：

• 1) Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowittz DM, Kopin IJ. 1983. A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA 80: 4546-4550.
• 2) Riederer P, Gille G, Muller T, Przuntek H, Reichmann H, Riess O, Schwarz A, Vogt T. 2002. Practical importance of neuroprotection in Parkinson's disease. J Neurol Suppl 3: III53-III56.
• 3) Riederer P, Foley P, Bringmann G, Feneis D, Bruckner R, Gerlach M. 2002. Biochemical and pharmacological characterization of 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline: a biologically relevant neurotoxin? Eur J Pharmacol 442: 1-16.
• 4) McNaught KS, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa C, Jenner P, Marsden CD. 1998. Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease. Biochem Pharmacol 56: 921-933.
• 5) Iida H. 1988. Studies on the accumulation of dimethyl-β-propiothetin and the formation of dimethyl sulfide in aquatic organisms. Bull Tokai Teg Fish Res Lab 124: 35-111 (in Japanese).

Terms in the title (5)： マウス ,  フェニル ,  誘導 ,  パーキンソン病 ,  改善効果