Art

J-GLOBAL ID：200902212152899890   Reference number：05A0360733

Study of blood metabolism and urinary excretion of chymopapain following intradiscal injection using a high-sensitivity enzyme immunoassay

椎間板内注射後のキモパパインの血中代謝と尿中排せつに関する高感度酵素免疫測定法を用いた研究

Author (4)： KAWANO Keiichiro (Matsubashikawano Orthopaedic Hospital, Miyazaki, JPN) ,  TAJIMA Naoya (Univ. Miyazaki, Miyazaki, JPN) ,  HASHIDA Seiichi (Tokushima Bunri Univ., Tokushima, JPN) ,  ISHIKAWA Eiji (Univ. Miyazaki, Miyazaki, JPN)
Material： Journal of Orthopaedic Science  (J Orthop Sci)
Volume： 10  Issue： 2  Page： 206-213  Publication year： 2005 
JST Material Number： L3245A  ISSN： 0949-2658  CODEN： JOSCFS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： dog ,...
Semi thesaurus term： 椎間板内投与 ,...

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JST classification (4)： Drug therapy(=pharmacotherapy)for musculoskeletal diseases  (GG05020D) ,  Basic medicine on musculoskeletal system  (GG01020B) ,  Clinical application of enzyme preparations and inhibitor preparations  (GW21020H) ,  Bioassay  (EA03060N)

Reference (18)：

• BROWN, MD. Update on chemonucleolysis. Spine. 1996, 21, 62S-68S
• BUTTLE, DJ. The biochemistry of the action of chymopapain in relief of sciatica. Spine. 1986, 11, 688-694
• EBATA, M. Isolation, crystallization, and preliminary characterization. J Biol Chem. 1962, 237, 1086-1094
• FUKUSHIMA, K. Metabolic fate of chymopapain in rats and rabbits. Clin Rep. 1989, 23, 77-90
• INOUE, S. Assessment of treatment of low back pain. J Jpn Orthop Assoc. 1986, 60, 905-911

Terms in the title (9)： 椎間板 ,  注射 ,  キモパパイン ,  血 ,  代謝 ,  尿中排せつ ,  高感度 ,  酵素免疫測定法 ,  研究