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J-GLOBAL ID：200902212154589030   Reference number：08A0499794

Mitochondrial changes in motor neurons of homozygotes of leucine 126 TT deletion SOD1 transgenic mice

ロイシン126TT欠失SOD1トランスジェニックマウスのホモ接合体における運動ニューロンのミトコンドリア変化

Author (10)： DOI Koji (Tottori Univ., Yonago, JPN) ,  NAKANO Toshiya (Tottori Univ., Yonago, JPN) ,  KITAYAMA Michio (Tottori Univ., Yonago, JPN) ,  WATANABE Yasuhiro (Tottori Univ., Yonago, JPN) ,  YASUI Kenichi (Tottori Univ., Yonago, JPN) ,  FUKADA Yasuyo (Tottori Univ., Yonago, JPN) ,  MORINO Shinichi (Tottori Univ., Yonago, JPN) ,  KAIDOH Toshiyuki (Tottori Univ., Yonago, JPN) ,  NAKASHIMA Kenji (Tottori Univ., Yonago, JPN) ,  INOUE Takao (Tottori Univ., Yonago, JPN)
Material： Neuropathology
Volume： 28  Issue： 3  Page： 269-276  Publication year： Jun. 2008 
JST Material Number： W0751A  ISSN： 0919-6544  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： transgenic mouse ,...
Semi thesaurus term： *SOD1

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JST classification (2)： Basic medicine on musculoskeletal system  (GG01020B) ,  Basic neurology  (GN01020W)

Reference (27)：

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• NAGAI, M. Rats expressing human cytosolic Copper-Zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis : associated mutations develop motor neuron disease. J Neurosci. 2001, 23, 9246-9254
• ROSEN, DR. Mutations in Cu/Zn superoxide dismutase are associated with familial amyotrophic lateral sclerosis. Nature. 1993, 362, 59-62
• TAKAHASHI, K. Hereditary amyotrophic lateral sclerosis : histochemical and electron microscopic study of hyaline inclusions in motor neurons. Arch Neurol. 1972, 27, 292-299
• WATANABE, Y. Mouse motor neuron disease caused by truncated SOD1 with or without C-terminal modification. Mol Brain Res. 2005, 135, 12-20

Terms in the title (7)： ロイシン ,  欠失 ,  SOD1 ,  トランスジェニックマウス ,  ホモ接合体 ,  運動ニューロン ,  ミトコンドリア