Art

J-GLOBAL ID：200902212898340545   Reference number：09A0347677

Regio- and Chemoselective Metalation of Chloropyrimidine Derivatives with TMPMgClLiCl and TMP₂Zn 2 MgCl₂ 2 LiCl

クロロピリミジン誘導体のTMPMgCl・LiClおよびTMP₂Zn・2MgCl₂・2LiClによる位置特異的および化学選択的金属化

Author (2)： MOSRIN Marc (Ludwig-Maximilians Univ. Muenchen, Muenchen, DEU) ,  KNOCHEL Paul (Ludwig-Maximilians Univ. Muenchen, Muenchen, DEU)
Material： Chemistry - European Journal  (Chem Eur J)
Volume： 15  Issue： 6  Page： 1468-1477  Publication year： 2009 
JST Material Number： W0744A  ISSN： 0947-6539  CODEN： CEUJED  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *organomagnesium compound ,  *organozinc compound ,  *nitrogen heterocyclic compound ,  *aromatic chlorine compound ,  *metallization(IC) ,  regiospecific reaction ,  substitution reaction ,  functionalization ,  amination ,  electrophilic reaction
Semi thesaurus term： *chloropyrimidine derivative ,  Pyrimidines ,  metallization ,  electrophilic reaction

JST classification (3)： Group 11 and group 12 organic compounds  (CF09052N) ,  Nitrogen heterocycles in general  (CF07040G) ,  Regiochemistry of organic reaction  (CF02140G)

Substance index (15)： 4,6-Dichloro-2-(methylthio)-5-(chloromagnesio)pyrimidine ,  Bis(4,6-dichloro-5-pyrimidinyl) zinc ,  4,6-Dichloro-2,5-diiodopyrimidine ,  Bis(2,5-dichloro-4-pyrimidinyl) zinc ,  2-Chloro-6-(methylthio)-4-(chloromagnesio)pyrimidine ,  4-Chloro-3-(4-fluorophenyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine ,  4-Chloro-3-(2,2-dimethylpropyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine ,  4-Chloro-3-phenyl-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine ,  4,6-Dichloro-2-(methylthio)-5-morpholinopyrimidine ,  4,6-Dichloro-2-(methylthio)-5-(1-methylpiperazine-4-yl)pyrimidine ,  4,6-Dichloro-2-(methylthio)-5-piperidinopyrimidine ,  Mepanipyrim ,  4,6-Dichloro-5-bromo-2-(methylthio)pyrimidine ,  5-Benzoyl-4,6-dichloro-2-(methylthio)pyrimidine ,  2,4,6-Trichloro-5-allylpyrimidine

Terms in the title (3)： ピリミジン誘導体 ,  化学 ,  金属化