Art
J-GLOBAL ID：200902213394894210
Reference number：04A0459357
Toborinone and olprinone, phosphodiesterase III inhibitors, inhibit human platelet aggregation due to the inhibition of both calcium release from intracellular stores and calcium entry
ホスホジエステラーゼ3阻害剤であるトボリノンとオルプリノンによる,細胞内貯蔵からのカルシウム放出とカルシウム流入の両者の阻害によるヒト血小板凝集の阻害
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Material：
Volume：
18
Issue：
2
Page：
107-112
Publication year：
May. 20, 2004
JST Material Number：
L0489A
ISSN：
0913-8668
CODEN：
JANEEC
Document type：
Article
Article type：
原著論文
Country of issue：
Germany, Federal Republic of (DEU)
Language：
ENGLISH (EN)
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Thesaurus term/Semi thesaurus term
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JST classification (1)：
JST classification
Category name(code) classified by JST.
Basic research of enzyme preparations and enzyme inhibitor preparations
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Substance index
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Reference (22)：
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HIRATA, T. Study on the effectiveness of toborinone (OPC-18790) in the treatment of heart failure in patients following cardiac surgery. Arzneimittelforschung. 1999, 9, 499-503
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SEMENIUK, LM. Acute effects of toborinone on vascular capacitance and conductance in experimental heart failure. Circulation. 1998, 98, 58-63
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MURAKAMI, R. Effects of intracoronary infusion of an inotropic agent, E-1020 (loprinone hydrochloride), on cardiac function : evaluation of left ventricular contractile performance using the end-systolic pressure-volume relationship. Int J Cardiol. 1995, 51, 57-63
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PATELUNAS, DM. Comparative antithrombotic activities of the phosphodiesterase inhibitors pelrinone (AY-26,768), AY-31,390 and milrinone. Thromb Res Suppl. 1991, 62, 389-400
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HIRAMATSU, N. Anti-thrombotic effect of milrinone is caused by inhibition of calcium release from the dense tubular system in human platelets. Acta Anesthesiol Scand. 2003, 47, 53-57
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