Art

J-GLOBAL ID：200902214994397062   Reference number：05A0565585

Increased cytoprotective function in the liver of transgenic mice expressing osteopontin in hepatocytes

肝細胞にオステオポンチンを発現している遺伝子導入マウス肝に於ける上昇した細胞保護機能

Author (10)： KOH Hea Saeng (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  MATSUI Atsushi (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  MIMURA Sumie (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  INAO Mie (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  SAITOH Eiko (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  OHNO Akihiko (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  NAGOSHI Sumiko (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  YOSHIMOTO Takayuki (Intractable Disease Res. Center, Tokyo Medical Univ., Tokyo, JPN) ,  MOCHIDA Satoshi (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN) ,  FUJIWARA Kenji (Div. of Gastroenterology & Hepatology, Internal Medicine, Saitama Medical School, Saitama, JPN)
Material： Hepatology Research  (Hepatol Res)
Volume： 32  Issue： 1  Page： 46-51  Publication year： May. 2005 
JST Material Number： W1284A  ISSN： 1386-6346  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： gene introduction ,...
Semi thesaurus term： immunological reaction

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JST classification (1)： Digestive system diseases  (GH03000W)

Reference (21)：

• CERNY, A. Pathogenesis of chronic hepatitis C : immunological features of hepatic injury and viral persistence. Hepatology. 1999, 30, 595-601
• ANDO, K. Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med. 1993, 178, 1541-1554
• KASAHARA, S. Lack of tumor necrosis factor alpha induces impaired proliferation of hepatitis B virus-specific cytotoxic T lymphocytes. J Virol. 2003, 77, 2469-2476
• BUTLER, WT. The nature and significance of osteopontin. Connect Tissue Res. 1989, 23, 123-136
• UEDE, T. Osteopontin, a coordinator of host defense system : a cytokine or an extracellular adhesive protein?. Microbiol Immunol. 1997, 41, 641-648

Terms in the title (7)： 肝細胞 ,  オステオポンチン ,  発現 ,  遺伝子導入 ,  マウス ,  肝 ,  細胞保護機能