Art

J-GLOBAL ID：200902215103381221   Reference number：06A0515668

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

CpG島メチル化形質は散発性のマイクロサテライト不安定性の原因であり,大腸がんのBRAF変異と密接に関連している

Author (21)： WEISENBERGER Daniel J (Univ. Southern California, California, USA) ,  SIEGMUND Kimberly D (Univ. Southern California, California, USA) ,  CAMPAN Mihaela (Univ. Southern California, California, USA) ,  YOUNG Joanne (Queensland Inst. of Medical Res., Queensland, AUS) ,  LONG Tiffany I (Univ. Southern California, California, USA) ,  FAASSE Mark A (Univ. Southern California, California, USA) ,  KANG Gyeong Hoon (Seoul National Univ. Hospital, Seoul, KOR) ,  WIDSCHWENDTER Martin (Univ. Coll. London, London, GBR) ,  WEENER Deborah (Univ. Southern California, California, USA) ,  BUCHANAN Daniel (Queensland Inst. of Medical Res., Queensland, AUS) ,  KOH Hoey (Royal Brisbane & Women’s Hospital Res. Foundation, Queensland, AUS) ,  SIMMS Lisa (Royal Brisbane & Women’s Hospital Res. Foundation, Queensland, AUS) ,  BARKER Melissa (Queensland Inst. of Medical Res., Queensland, AUS) ,  LEGGETT Barbara (Royal Brisbane & Women’s Hospital Res. Foundation, Queensland, AUS) ,  LEVINE Joan (Univ. Southern California, California, USA) ,  KIM Myungjin (Univ. Southern California, California, USA) ,  FRENCH Amy J (Mayo Clinic and Foundation, Minnesota, USA) ,  THIBODEAU Stephen N (Mayo Clinic and Foundation, Minnesota, USA) ,  JASS Jeremy (McGill Univ., QC Canada) ,  HAILE Robert (Univ. Southern California, California, USA) ,  LAIRD Peter W (Univ. Southern California, California, USA)
Material： Nature Genetics  (Nat Genet)
Volume： 38  Issue： 7  Page： 787-793  Publication year： Jul. 10, 2006 
JST Material Number： W0430A  ISSN： 1061-4036  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *colorectal neoplasm ,...
Semi thesaurus term： CpG island ,...

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JST classification (1)： Genetic variation  (EC01030Y)

Terms in the title (8)： CpG島 ,  メチル化 ,  形質 ,  マイクロサテライト不安定性 ,  原因 ,  大腸がん ,  BRAF ,  変異