Art

J-GLOBAL ID：200902215642619223   Reference number：07A0018401

Granulocyte Colony-Stimulating Factor Prevents Progression of Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

顆粒球コロニー刺激因子はラットにおいてモノクロタリン誘導肺動脈高血圧の進行を抑制する

Author (8)： MARUYAMA Hidekazu (Dep. of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  WATANABE Shigeyuki (Dep. of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  KIMURA Taizo (Dep. of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  LIANG Jingyan (Dep. of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  NAGASAWA Toshiro (Div. of Clinical and Experimental Hematology, Major of Advanced Biochemical Applications, Graduate School of ...) ,  ONODERA Masafumi (Div. of Clinical and Experimental Hematology, Major of Advanced Biochemical Applications, Graduate School of ...) ,  AONUMA Kazutaka (Dep. of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  YAMAGUCHI Iwao (Dep. of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba)
Material： Circulation Journal  (Circ J)
Volume： 71  Issue： 1  Page： 138-143 (J-STAGE)  Publication year： 2007 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Rattus ,...
Semi thesaurus term： remediation strategy ,...

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JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： Monocrotaline

Reference (24)：

• 1. Giaid A, Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med 1995; 333: 214-221.
• 2. Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, Stewart DJ. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: Efficacy of combined cell and eNOS gene therapy in established disease. Circ Res 2005; 96: 442-450.
• 3. Nagaya N, Kangawa K, Kanda M, Uematsu M, Horio T, Fukuyama N, et al. Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells. Circulation 2003; 108: 889-895.
• 4. Bussolino F, Wang JM, Defilippi P, Turrini F, Sanavio F, Edgell CJ, et al. Granulocyte-and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. Nature 1989; 337: 471-473.
• 5. Bussolino F, Ziche M, Wang JM, Alessi D, Morbidelli L, Cremona O, et al. In vitro and in vivo activation of endothelial cells by colony-stimulating factors. J Clin Invest 1991; 87: 986-995.

Terms in the title (5)： 顆粒球コロニー刺激因子 ,  ラット ,  モノクロタリン ,  誘導 ,  肺動脈高血圧