Art

J-GLOBAL ID：200902215869315387   Reference number：09A0820418

Accurate Determination of Carboxyl-Terminal Fragment of Presenilin 1 in Various Tissues from Rat and Cell Lines

ラット由来の種々の組織及び細胞系におけるプレセニリン1のカルボキシル末端断片の正確な定量

Author (2)： CHAI Hui Lin (Yokohama City Univ. School of Medicine, Yokohama, JPN) ,  MIURA Satoshi (Yokohama City Univ. School of Medicine, Yokohama, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 146  Issue： 1  Page： 141-148  Publication year： Jul. 01, 2009 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *presenilin ,...

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JST classification (3)： Proteins and peptides in general  (EB03010N) ,  Animal biochemistry  (EJ01050P) ,  Nervous system diseases  (GN03000O)

Reference (29)：

• VASSAR, R. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 1999, 286, 735-741
• SHERRINGTON, R. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 1995, 375, 754-760
• ROGAEV, E. I. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 1995, 376, 775-778
• DE STROOPER, B. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature. 1998, 391, 387-390
• ZHANG, Z. Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nat. Cell Biol. 2000, 2, 463-465

Terms in the title (7)： ラット ,  組織 ,  細胞系 ,  プレセニリン1 ,  カルボキシル末端 ,  断片 ,  定量