Art

J-GLOBAL ID：200902217199712064   Reference number：08A0465787

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

統合失調症において希な構造的変異体が神経発達経路の多数の遺伝子を崩壊する

Author (37)： WALSH Tom (Univ. Washington, WA, USA) ,  MCCLELLAN Jon M. (Univ. Washington, WA, USA) ,  MCCARTHY Shane E. (Cold Spring Harbor Lab., NY, USA) ,  ADDINGTON Anjene M. (National Inst. Health (NIH), MD, USA) ,  PIERCE Sarah B. (Univ. Washington, WA, USA) ,  COOPER Greg M. (Univ. Washington, WA, USA) ,  NORD Alex S. (Univ. Washington, WA, USA) ,  KUSENDA Mary (Cold Spring Harbor Lab., NY, USA) ,  KUSENDA Mary (State Univ. New York, NY, USA) ,  MALHOTRA Dheeraj (Cold Spring Harbor Lab., NY, USA) ,  BHANDARI Abhishek (Cold Spring Harbor Lab., NY, USA) ,  STRAY Sunday M. (Univ. Washington, WA, USA) ,  RIPPEY Caitlin F. (Univ. Washington, WA, USA) ,  ROCCANOVA Patricia (Cold Spring Harbor Lab., NY, USA) ,  MAKAROV Vlad (Cold Spring Harbor Lab., NY, USA) ,  LAKSHMI B. (Cold Spring Harbor Lab., NY, USA) ,  FINDLING Robert L. (Case Medical Center, OH, USA) ,  SIKICH Linmarie (Univ. North Carolina, NC, USA) ,  STROMBERG Thomas (National Inst. Health (NIH), MD, USA) ,  MERRIMAN Barry (Univ. California, CA, USA) ,  GOGTAY Nitin (National Inst. Health (NIH), MD, USA) ,  BUTLER Philip (National Inst. Health (NIH), MD, USA) ,  ECKSTRAND Kristen (National Inst. Health (NIH), MD, USA) ,  NOORY Laila (National Inst. Health (NIH), MD, USA) ,  GOCHMAN Peter (National Inst. Health (NIH), MD, USA) ,  LONG Robert (National Inst. Health (NIH), MD, USA) ,  CHEN Zugen (Univ. California, CA, USA) ,  DAVIS Sean (National Inst. Health (NIH), MD, USA) ,  BAKER Carl (Univ. Washington, WA, USA) ,  EICHLER Evan E. (Univ. Washington, WA, USA) ,  MELTZER Paul S. (National Inst. Health (NIH), MD, USA) ,  NELSON Stanley F. (Univ. California, CA, USA) ,  SINGLETON Andrew B. (National Inst. Health (NIH), MD, USA) ,  LEE Ming K. (Univ. Washington, WA, USA) ,  RAPOPORT Judith L. (National Inst. Health (NIH), MD, USA) ,  KING Mary-Claire (Univ. Washington, WA, USA) ,  SEBAT Jonathan (Cold Spring Harbor Lab., NY, USA)
Material： Science
Volume： 320  Issue： 5875  Page： 539-543  Publication year： Apr. 25, 2008 
JST Material Number： E0078A  ISSN： 0036-8075  CODEN： SCIEA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *schizophrenia ,  *mutant ,  DNA microarray ,  molecular hybridization ,  Gene Duplication ,  deletion mutation ,  gene frequency ,  neurotrophic factor ,  growth factor ,  nucleotide sequence ,  *gene disruption ,  *Nervous System ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  dicarboxylic acid ,  primary amine ,  Neuregulins ,  *Signal Transduction ,  molecular genetic phenomenon ,  Heredity ,  population genetics ,  factor ,  bioactive factor
Semi thesaurus term： *cellular signal transduction

JST classification (2)： Nervous system diseases  (GN03000O) ,  Structure and chemistry of genes  (EC02020U)

Substance index (1)： Glutamic acid

Terms in the title (6)： 統合失調症 ,  変異体 ,  神経発達 ,  経路 ,  遺伝子 ,  崩壊