Art

J-GLOBAL ID：200902217816413100   Reference number：09A0235754

Nicorandil Attenuates FeCl₃-Induced Thrombus Formation Through the Inhibition of Reactive Oxygen Species Production

ニコランジルは反応性酸素分子種生産阻害を介しFeCl₃誘導血栓形成を抑制する

Author (7)： EGUCHI Yu (Dep. of Physiology, Tokai Univ. School of Medicine) ,  TAKAHARI Youko (Teaching and Res. Support Center, Tokai Univ. School of Medicine) ,  HIGASHIJIMA Naoko (Dep. of Physiology, Tokai Univ. School of Medicine) ,  ISHIZUKA Nobuhiko (Fuji Gotemba Res. Laboratories, Chugai Pharmaceutical Co Ltd) ,  TAMURA Noriko (Dep. of Internal Medicine, Tokai Univ. School of Medicine) ,  KAWAMURA Yota (Dep. of Internal Medicine, Tokai Univ. School of Medicine) ,  ISHIDA Hideyuki (Dep. of Physiology, Tokai Univ. School of Medicine)
Material： Circulation Journal  (Circ J)
Volume： 73  Issue： 3  Page： 554-561 (J-STAGE)  Publication year： 2009 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： vasodilator ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=09A0235754&from=J-GLOBAL&jstjournalNo=F0908A") }}

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (5)： Nicorandil ,  Tirofiban ,  Diazoxide ,  Isosorbide dinitrate ,  L-NAME

Reference (33)：

• 1. Cai H. Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences. Cardiovasc Res 2005; 68: 26-36.
• 2. Heistad DD. Oxidative stress and vascular disease [2005 Duff lecture]. Arterioscler Thromb Vasc Biol 2006; 26: 689-695.
• 3. Sekiya M, Sato M, Funada J, Ohtani T, Akutsu H, Watanabe K. Effects of the long-term administration of nicorandil on vascular endothelial function and the progression of arteriosclerosis. J Cardiovasc Pharmacol 2005; 46: 63-67.
• 4. Ishibashi Y, Takahashi N, Tokumaru A, Karino K, Sugamori T, Sakane T, et al. Effects of long-term nicorandil administration on endothelial function, inflammation, and oxidative stress in patients without coronary artery disease. J Cardiovasc Pharmacol 2008; 51: 311-316.
• 5. O'Rourke B. Myocardial KATP channels in preconditioning. Circ Res 2000; 87: 845-855.

Terms in the title (6)： ニコランジル ,  反応性酸素分子種 ,  阻害 ,  FeCl3 ,  誘導 ,  血栓形成