Art

J-GLOBAL ID：200902217944897101   Reference number：05A0760366

Luteolin Inhibits Endothelin-1 Secretion in Cultured Endothelial Cells

ルテオリンは培養内皮細胞におけるエンドセリン1分泌を阻害する

Author (8)： KOZAKAI Takaharu (Inst. for Biological Resources and Functions, National Inst. of Advanced Industrial Sci. and Technol.) ,  YAMANAKA Akiko (Inst. for Biological Resources and Functions, National Inst. of Advanced Industrial Sci. and Technol.) ,  ICHIBA Toshio (Okinawa Industrial Technol. Center) ,  TOYOKAWA Tetsuya (Okinawa Industrial Technol. Center) ,  KAMADA Yasuhiro (Okinawa Industrial Technol. Center) ,  TAMAMURA Takako (Okinawa Industrial Technol. Center) ,  ICHIMURA Toshiaki (Inst. for Biological Resources and Functions, National Inst. of Advanced Industrial Sci. and Technol.) ,  MARUYAMA Susumu (Inst. for Biological Resources and Functions, National Inst. of Advanced Industrial Sci. and Technol.)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 69  Issue： 8  Page： 1613-1615 (J-STAGE)  Publication year： 2005 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *flavonoid ,...

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JST classification (1)： Vasculature  (EJ04030O)

Substance index (2)： Endothelin-1 ,  Luteolin

Reference (8)：

• 1) Kinlay, S., Behrendt, D., and Wainstein, M., Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries. Circulation, 104, 1114–1118 (2001).
• 2) Corder, R., Identity of endothelin-converting enzyme and other targets for the therapeutic regulation of endothelin biosynthesis. Handb. Exp. Pharmacol., 152, 35–67 (2001).
• 3) Fitzpatrick, D. F., Hirschfield, S. L., and Coffey, R. G., Endothelium-dependent vasorelaxing activity of wine and grape products. Am. J. Physiol., 265, H774–778 (1993).
• 4) Corder, R., Douthwaite, J. A., Lees, D. M., Khan, N. Q., dos Santos, A. C. V., Wood, E. G., and Carrier, M. L., Endothelin-1 synthesis reduced by red wine. Nature, 414, 863–864 (2001).
• 5) Khan, N. Q., Lees, D. M., Douthwaite, J. A., Carrier, M. J., and Corder, R., Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells. Clin. Sci., 103, 72S–75S (2002).

Terms in the title (6)： ルテオリン ,  培養 ,  内皮細胞 ,  エンドセリン1 ,  分泌 ,  阻害