Art

J-GLOBAL ID：200902218367760254   Reference number：04A0685484

Involvement of Peripheral Mechanism in the Verapamil-Induced Potentiation of Morphine Analgesia in Mice

マウスにおいてベラパミルが誘導するモルヒネ鎮痛の増強に関する末梢機構の関与

Author (8)： SHIMIZU N (Wakayama Medical Univ., Wakayama, JPN) ,  KISHIOKA S (Wakayama Medical Univ., Wakayama, JPN) ,  MAEDA T (Wakayama Medical Univ., Wakayama, JPN) ,  FUKAZAWA Y (Wakayama Medical Univ., Wakayama, JPN) ,  DAKE Y (Wakayama Medical Univ., Wakayama, JPN) ,  YAMAMOTO C (Wakayama Medical Univ., Wakayama, JPN) ,  OZAKI M (Niigata Univ. Pharmacy and Applied Life Sci., Niigata, JPN) ,  YAMAMOTO H (Wakayama Medical Univ., Wakayama, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 95  Issue： 4  Page： 452-457  Publication year： Aug. 20, 2004 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： calcium channel blocker ,...

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JST classification (3)： Basic research of addictive analgesics and narcotics  (GW03080Z) ,  Basic neurology  (GN01020W) ,  Receptors on cell membrane  (EF04030C)

Substance index (4)： Morphine ,  Verapamil ,  Naloxone ,  Corticosterone

Reference (31)：

• 1 Barber A, Gottschlich R. Opioid agonists and antagonists: an evaluation of their peripheral actions in inflammation. Med Res Rev. 1992;12:525–562.
• 2 Joris JL, Dubner R, Hargreaves KM. Opioid analgesia at peripheral sites: a target for opioids released during stress and inflammation? Anesth Analg. 1987;66:1277–1281.
• 3 Junien JL, Wettstein JG. Role of opioids in peripheral analgesia. Life Sci. 1992;51:2009–2018.
• 4 Kayser V, Lee SH, Guilbaud G. Evidence for a peripheral component in the enhanced antinociceptive effect of a low dose of systemic morphine in rats with peripheral mononeuropathy. Neuroscience. 1995;64:537–545.
• 5 Kolesnikov YA, Jain S, Wilson R, Pasternak GW. Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance. J Pharmacol Exp Ther. 1996;279:502–506.

Terms in the title (6)： マウス ,  ベラパミル ,  誘導 ,  モルヒネ ,  鎮痛 ,  増強