Art

J-GLOBAL ID：200902219604964133   Reference number：08A0029783

An Improved Mouse Model of Atopic Dermatitis and Suppression of Skin Lesions by an Inhibitor of Tec Family Kinases

マウスアトピー性皮膚炎改良モデルおよびTecファミリーキナーゼ阻害薬による皮膚病変の抑制

Author (5)： KAWAKAMI Yuko (Div. of Cell Biology, La Jolla Inst. for Allergy and Immunology) ,  KAWAKAMI Yuko (Allimmune, LLC) ,  YUMOTO Kenji (Div. of Cell Biology, La Jolla Inst. for Allergy and Immunology) ,  KAWAKAMI Toshiaki (Div. of Cell Biology, La Jolla Inst. for Allergy and Immunology) ,  KAWAKAMI Toshiaki (Allimmune, LLC)
Material： Allergology International  (Allergol Int)
Volume： 56  Issue： 4  Page： 403-409 (J-STAGE)  Publication year： 2007 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： Tecファミリーキナーゼ阻害薬

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JST classification (1)： Basic dermatology  (GF01020Y)

Substance index (2)： Dexamethasone ,  Terreic acid

Reference (33)：

• LEUNG, DY. New insights into atopic dermatitis. J. Clin. Invest. 2004, 113, 651-657
• WOLLENBERG, A. Atopic dermatitis : from the genes to skin lesions. Allergy. 2000, 55, 205-213
• GREWE, M. A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis. Immunol. Today. 1998, 19, 359-361
• TSICOPOULOS, A. Kinetics of cell infiltration and cytokine messenger RNA expression after intradermal challenge with allergen and tuberculin in the same atopic individuals. J. Allergy Clin. Immunol. 1994, 94, 764-772
• WERFEL, T. Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitis. J. Invest. Dermatol. 1996, 107, 871-876

Terms in the title (8)： マウス ,  アトピー性皮膚炎 ,  モデル ,  Tec ,  ファミリー ,  キナーゼ ,  阻害薬 ,  皮膚病変