Art

J-GLOBAL ID：200902219677956961   Reference number：08A0126450

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

β細胞は損傷成体マウス脾臓における内因性前駆体から産生し得る

Author (31)： XU Xiaobo (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  XU Xiaobo (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  D'HOKER Joke (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  D'HOKER Joke (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  STANGE Geert (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  STANGE Geert (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  BONNE Stefan (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  BONNE Stefan (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  DE LEU Nico (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  DE LEU Nico (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  XIAO Xiangwei (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  XIAO Xiangwei (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  VAN DE CASTEELE Mark (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  VAN DE CASTEELE Mark (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  MELLITZER Georg (INSERM, U682, Dev. and Physiopathology of the Intestine and Pancreas, 67200 Strasbourg, FRA) ,  MELLITZER Georg (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  LING Zhidong (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  LING Zhidong (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  PIPELEERS Danny (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  PIPELEERS Danny (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  BOUWENS Luc (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  BOUWENS Luc (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  SCHARFMANN Raphael (INSERM, U845, Fac. of Medicine Necker, 75730 Paris, FRA) ,  SCHARFMANN Raphael (Beta Cell Biology Consortium, 2213 Garland Avenue, 9465 MRB IV, Nashville, TN 37323-0494, USA) ,  SCHARFMANN Raphael (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  GRADWOHL Gerard (INSERM, U682, Dev. and Physiopathology of the Intestine and Pancreas, 67200 Strasbourg, FRA) ,  GRADWOHL Gerard (Beta Cell Biology Consortium, 2213 Garland Avenue, 9465 MRB IV, Nashville, TN 37323-0494, USA) ,  GRADWOHL Gerard (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL) ,  HEIMBERG Harry (Diabetes Res. Center, Vrije Universiteit Brussel, Laarbeeklaan 103, B1090 Brussels, BEL) ,  HEIMBERG Harry (Beta Cell Biology Consortium, 2213 Garland Avenue, 9465 MRB IV, Nashville, TN 37323-0494, USA) ,  HEIMBERG Harry (JDRF Center for Beta Cell Therapy in Diabetes, Laarbeeklaan 103, B1090 Brussels, BEL)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 132  Issue： 2  Page： 197-207  Publication year： Jan. 25, 2008 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Langerhans islet ,  mouse(animal) ,  diabetes mellitus ,  precursor(substance) ,  transcription factor ,  protein ,  *spleen ,  adult(development) ,  cell differentiation ,  *morphogenesis ,  biomarker
Semi thesaurus term： *pancreas beta cell ,  beta cell progenitors ,  Neurogenin 3 ,  *Organogenesis

JST classification (2)： Biological function  (EB03040U) ,  Physiology of development(=generation)in general  (EJ16010L)

Terms in the title (7)： β細胞 ,  損傷 ,  成体 ,  マウス ,  脾臓 ,  内因性 ,  前駆体