Art

J-GLOBAL ID：200902220274014352   Reference number：03A0248083

Formaldehyde-Induced Shrinkage of Rat Thymocytes.

ラット胸腺細胞のホルムアルデヒド誘起縮小

Author (7)： NAKAO H (Univ. Tokushima, Tokushima, JPN) ,  UMEBAYASHI C (Univ. Tokushima, Tokushima, JPN) ,  NAKATA M (Univ. Tokushima, Tokushima, JPN) ,  NISHIZAKI Y (Univ. Tokushima, Tokushima, JPN) ,  NODA K (Univ. Tokushima, Tokushima, JPN) ,  OKANO Y (Tokushima Bunri Univ., Tokushima, JPN) ,  OYAMA Y (Univ. Tokushima, Tokushima, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 91  Issue： 1  Page： 83-86  Publication year： Jan. 01, 2003 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *aliphatic aldehyde ,...
Semi thesaurus term： 細胞縮小

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JST classification (2)： Toxicity of organic compounds  (GZ02030Y) ,  Food chemistry,nutritional value  (FJ01020J)

Substance index (3)： Aspartame ,  Formaldehyde ,  Methanol

Reference (13)：

• 1 Ranney RE, Oppermann JA, Muldoon E and McMahon FG: Comparative metabolism of aspartame in experimental animals and humans. J Toxicol Environ Health 2, 441 – 451 (1976)
• 2 Stegink LD, Brummel MC, McMartin K, Martin-Amat G, Filer LJ, Baker GL and Tephly TR: Blood methanol concentrations in normal adult subjects administered abuse doses of aspartame. J Toxicol Environ Health 7, 281 – 290 (1981)
• 3 Oyama Y, Sakai H, Arata T, Okano Y, Akaike N, Sakai K and Noda K: Cytotoxic effects of methanol, formaldehyde, and formate on dissociated rat thymocytes: A possibility of aspartame toxicity. Cell Biol Toxicol 18, 43 – 50 (2002)
• 4 Leon AS, Hunnighake DB, Bell C, Rassin DK and Tephly TR: Safety of long-term large doses of aspartame. Arch Intern Med 149, 2318 – 2324 (1989)
• 5 Maeno E, Ishizaki Y, Kanaseki T, Hazama A and Okada Y: Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci USA 97, 9487 – 9492 (2000)

Terms in the title (5)： ラット ,  胸腺細胞 ,  ホルムアルデヒド ,  誘起 ,  縮小