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J-GLOBAL ID：200902221244016420
Reference number：04A0797955
Phase I/II study of irinotecan, 5-fluorouracil, and l-leucovorin combination therapy (modified Saltz regimen) in patients with metastatic colorectal cancer
転移直腸結腸癌患者に対するイリノテカン,5-フルオロウラシルおよびl-ロイコボリン併用療法(改変Saltz処方)の第I相/第II相試験
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Author (9)：
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Material：
Volume：
9
Issue：
5
Page：
364-368
Publication year：
Oct. 2004
JST Material Number：
L3966A
ISSN：
1341-9625
Document type：
Article
Article type：
原著論文
Country of issue：
Germany, Federal Republic of (DEU)
Language：
ENGLISH (EN)
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Clinical application of antitumor(=antineoplastic)drugs
, Drug therapy(=pharmacotherapy)for tumors
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Reference (14)：
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The Advanced Colorectal Cancer Meta-Analysis Project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer : evidence in terms of response rate. J Clin Oncol. 1992, 10, 896-903
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CUNNINGHAM, D. Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet. 1998, 352, 1413-1418
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ROUGIER, P. Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet. 1998, 352, 1407-1412
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SALTZ, LB. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N Engl J Med. 2000, 343, 905-914
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DOUILLARD, JY. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer : a multicentre randomised trial. Lancet. 2000, 355, 1041-1047
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