Art

J-GLOBAL ID：200902221789867800   Reference number：05A0871232

The simple and selective synthesis of 3-amino-2,2-difluorocarboxylic esters and difluoro-β-lactams using ethyl bromodifluoroacetate in the presence of rhodium catalyst

ロジウム触媒存在下のブロモジフルオロ酢酸エチルを用いた3-アミノ-2,2-ジフルオロカルボン酸エステル及びジフルオロ-β-ラクタムの簡単な選択的合成

Author (6)： SATO Kazuyuki (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  TARUI Atsushi (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  MATSUDA Seiji (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  OMOTE Masaaki (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  ANDO Akira (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  KUMADAKI Itsumaro (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 46  Issue： 45  Page： 7679-7681  Publication year： Nov. 07, 2005 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *lactam ,...

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JST classification (1)： Four-membered heterocyclic compounds  (CF07060C)

Substance index (32)： Tetrahydrofuran ,  Ethyl bromodifluoroacetate ,  N-Phenylbenzenemethanimine ,  N-Benzylbenzenemethanimine ,  N-Benzyl-4-methoxybenzylideneamine ,  N-Benzyl-4-isopropylbenzenemethaneimine ,  N-(4-Chlorobenzylidene)benzylamine ,  4-(Benzyliminomethyl)benzoic acid methyl ester ,  N-Benzyl-4-nitrobenzylideneamine ,  N-Benzylcyclohexanemethanimine ,  N-Benzyl-2,2-dimethyl-1-propanimine ,  N-Methylbenzenemethanimine ,  N-tert-Butylbenzenemethanimine ,  N-Benzyl-1-phenylethane-1-imine ,  N-Benzyldiphenylmethyleneamine ,  Diethyl zinc ,  3,3-Difluoro-1,2-diphenylazetidine-4-one ,  1-Benzyl-3,3-difluoro-4-phenylazetidine-2-one ,  1-Benzyl-3,3-difluoro-4-(4-methoxyphenyl)azetidine-2-one ,  1-Benzyl-3,3-difluoro-4-(4-isopropylphenyl)azetidine-2-one ,  1-Benzyl-3,3-difluoro-4-(4-chlorophenyl)azetidine-2-one ,  4-(1-Benzyl-3,3-difluoro-4-oxoazetidine-2-yl)benzoic acid methyl ester ,  1-Benzyl-3,3-difluoro-4-(4-nitrophenyl)azetidine-2-one ,  1-Benzyl-3,3-difluoro-4-cyclohexylazetidine-2-one ,  1-Benzyl-3,3-difluoro-4-tert-butylazetidine-2-one ,  1-Methyl-3,3-difluoro-4-phenylazetidine-2-one ,  1-tert-Butyl-3,3-difluoro-4-phenylazetidine-2-one ,  1-Benzyl-3,3-difluoro-4-phenyl-4-methylazetidine-2-one ,  1-Benzyl-3,3-difluoro-4,4-diphenylazetidine-2-one ,  2,2-Difluoro-3-(benzylamino)-3-phenylpropionic acid ethyl ester ,  2,2-Difluoro-3-(benzylamino)-3-(4-methoxyphenyl)propionic acid ethyl ester ,  2,2-Difluoro-3-(benzylamino)-3-(4-chlorophenyl)propionic acid ethyl ester

Terms in the title (5)： ロジウム触媒 ,  ブロモジフルオロ酢酸エチル ,  酸 ,  エステル ,  β-ラクタム