Art

J-GLOBAL ID：200902221927053347   Reference number：08A0336769

RyR1 S-Nitrosylation Underlies Environmental Heat Stroke and Sudden Death in Y522S RyR1 Knockin Mice

RyR1のS-ニトロシル化はY522S RyR1ノックインマウスの環境的熱中症および突然死の基盤となる

Author (13)： DURHAM William J. (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA) ,  ARACENA-PARKS Paula (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA) ,  LONG Cheng (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA) ,  ROSSI Ann E. (Dep. of Pharmacology and Physiology, Univ. of Rochester Medical Center, Rochester, NY 14642, USA) ,  GOONASEKERA Sanjeewa A. (Dep. of Pharmacology and Physiology, Univ. of Rochester Medical Center, Rochester, NY 14642, USA) ,  BONCOMPAGNI Simona (Lab. of Cellular Physiology, CeSI Centro Scienze dell’Invecchiamento, Universita degli Studi G. d’Annunzio, Chieti ...) ,  GALVAN Daniel L. (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA) ,  GILMAN Charles P. (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA) ,  BAKER Mariah R. (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA) ,  SHIROKOVA Natalia (Dep. of Pharmacology and Physiology, UMDNJ, New Jersey Medical School, Newark, NJ 07103-2714, USA) ,  PROTASI Feliciano (Lab. of Cellular Physiology, CeSI Centro Scienze dell’Invecchiamento, Universita degli Studi G. d’Annunzio, Chieti ...) ,  DIRKSEN Robert (Dep. of Pharmacology and Physiology, Univ. of Rochester Medical Center, Rochester, NY 14642, USA) ,  HAMILTON Susan L. (Dep. of Molecular Physiology and Biophysics, Baylor Coll. of Medicine, Houston, TX 77030, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 133  Issue： 1  Page： 53-65  Publication year： Apr. 04, 2008 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *ryanodine receptor ,  substitution reaction ,  Mus musculus ,  laboratory animal ,  Heat Stroke ,  *Malignant Hyperthermia ,  experimental disease ,  mitochondrial disease ,  *hereditary disease ,  muscular disease ,  mineral metabolism ,  Genotype ,  oxidative stress ,  human ,  Western blotting ,  S-nitrosylation ,  calcium metabolism ,  knock-in mouse ,  Heterozygote ,  Myomorpha ,  dysfunction ,  disorder/trouble/obstacle ,  congenital disease ,  bioassay
Semi thesaurus term： Central core disease ,  *リアノジン受容体1 ,  heterozygote

JST classification (3)： Cell physiology in general  (EF02010S) ,  Muscles  (EJ10020G) ,  Congenital diseases,deformities in general.  (GD03010V)

Terms in the title (7)： RyR1 ,  S-ニトロシル化 ,  ノックインマウス ,  環境 ,  熱中症 ,  突然死 ,  基盤