Art

J-GLOBAL ID：200902222205074699   Reference number：09A0223716

Methionine-enkephalin secreted by human colorectal cancer cells suppresses T lymphocytes

ヒト大腸癌細胞により分泌されるメチオニン-エンケファリンはTリンパ球を抑制する

Author (7)： OHMORI Hitoshi (Nara Medical Univ., Kashihara, JPN) ,  FUJII Kiyomu (Nara Medical Univ., Kashihara, JPN) ,  SASAHIRA Tomonori (Nara Medical Univ., Kashihara, JPN) ,  LUO Yi (Nara Medical Univ., Kashihara, JPN) ,  ISOBE Mamoru (Nara Medical Univ., Kashihara, JPN) ,  TATSUMOTO Naokuni (Miyoshi Central Hospital, Miyoshi, JPN) ,  KUNIYASU Hiroki (Nara Medical Univ., Kashihara, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 100  Issue： 3  Page： 497-502  Publication year： Mar. 2009 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *colorectal neoplasm ,...
Semi thesaurus term： lymphatic tumor ,...

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JST classification (3)： Basic oncology in general  (GE02010R) ,  Bioactive peptides  (EB08100U) ,  Gene expression  (EC02040Q)

Substance index (1)： Methionine enkephalin

Reference (34)：

• KUNIYASU, H. Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages. Am J Pathol. 2005, 166, 751-760
• KUNIYASU, H. Depletion of tumor-infiltrating macrophages is associated with amphoterin expression in colon cancer. Pathobiology. 2004, 71, 129-136
• DONG, H. Tumor-associated B7-H1 promotes T-cell apoptosis : a potential mechanism of immune evasion. Nat Med. 2002, 8, 793-800
• NAKASHIMA, M. Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1. Nat Med. 1999, 5, 938-942
• OSHIKIRI, T. Tumor-associated antigen recognized by the 22-1-1 monoclonal antibody encourages colorectal cancer progression under the scanty CD8^+ T cells. Clin Cancer Res. 2006, 12, 411-416

Terms in the title (6)： ヒト ,  大腸癌細胞 ,  分泌 ,  メチオニン ,  エンケファリン ,  Tリンパ球