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J-GLOBAL ID：200902222465003841   Reference number：05A0967488

In vitro activity of β-lactams, macrolides, telithromycin, and fluoroquinolones against clinical isolates of Streptococcus pneumoniae: correlation between drug resistance and genetic characteristics

β-ラクタム,マクロライド,テリスロマイシンとフルオロキノロンの肺炎球菌の臨床分離株に対するin vitro活性 薬剤耐性と遺伝的性質の間の相関

Author (6)： YAMAGUCHI Toshiyuki (Saitama Medical School, Saitama, JPN) ,  HASHIKITA Giichi (Saitama Medical School, Saitama, JPN) ,  TAKAHASHI Shun (Saitama Medical School, Saitama, JPN) ,  ITABASHI Akira (Saitama Medical School, Saitama, JPN) ,  YAMAZAKI Tsutomu (Saitama Medical School, Saitama, JPN) ,  MAESAKI Shigefumi (Saitama Medical School, Saitama, JPN)
Material： Journal of Infection and Chemotherapy  (J Infect Chemother)
Volume： 11  Issue： 5  Page： 262-264  Publication year： Oct. 2005 
JST Material Number： L2852A  ISSN： 1341-321X  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： clinical isolate ,...
Semi thesaurus term： MIC(concentration) ,...

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JST classification (3)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C) ,  Microorganism physiology in general  (EG03051L) ,  Molecular genetics in general  (EC02010J)

Substance index (14)： Penicillin G ,  Ampicillin ,  Cefotiam ,  Cefepime ,  Cefditoren ,  Faropenem ,  Panipenem ,  Biapenem ,  Erythromycin ,  Clarithromycin ,  Azithromycin ,  Ciprofloxacin ,  Gatifloxacin ,  Levofloxacin

Reference (12)：

• SHIMADA, K. Susceptibilities of bacteria isolated from patients with lower respiratory infectious diseases to antibiotics. Jpn J Antibiot 2001. 54, 331-364
• UBUKATA, K. Antibiotic susceptibility in relation to penicillin-binding protein genes and serotype distribution of Streptococcus pneumoniae strains responsible for meningitis in Japan, 1999 to 2002. Antimicrob Agents Chemother. 2004, 48, 1488-1494
• MACGOWAN, AP. Establishing MIC breakpoints and the interpretation of in vitro susceptibility tests. J Antimicrob Chemother. 2001, 48, Suppl. S1, 17-28
• National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. Document M7-A5. 2000
• NAGAI, K. Evaluation of PCR primers to screen for Streptococcus pneumoniae isolates and beta-lactam resistance, and to detect common macrolide resistance determinants. J Antimicrob Chemother. 2001, 48, 915-918

Terms in the title (11)： β-ラクタム ,  マクロライド ,  テリスロマイシン ,  フルオロキノロン ,  肺炎球菌 ,  臨床分離株 ,  活性 ,  薬剤耐性 ,  遺伝 ,  性質 ,  相関