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J-GLOBAL ID：200902222704697443   Reference number：09A1187525

Structural Insights into the Enzymatic Mechanism of Serine Palmitoyltransferase from Sphingobacterium multivorum

Sphingobacterium multivorum由来のセリンパルミトイルトランスフェラーゼの酵素メカニズムへの構造的洞察

Author (11)： IKUSHIRO Hiroko (Osaka Medical Coll., Osaka, JPN) ,  ISLAM Mohammad Mainul (Osaka Medical Coll., Osaka, JPN) ,  ISLAM Mohammad Mainul (Wake Forest Univ. School of Medicine, NC, USA) ,  OKAMOTO Akihiro (Osaka Medical Coll., Osaka, JPN) ,  OKAMOTO Akihiro (Tokai Univ., Shizuoka) ,  HOSEKI Jun (Osaka Medical Coll., Osaka, JPN) ,  HOSEKI Jun (Kyoto Univ., Kyoto) ,  MURAKAWA Takeshi (Osaka Medical Coll., Osaka, JPN) ,  FUJII Shigeru (Kansai Medical Univ., Osaka) ,  MIYAHARA Ikuko (Osaka City Univ., Osaka, JPN) ,  HAYASHI Hideyuki (Osaka Medical Coll., Osaka, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 146  Issue： 4  Page： 549-562  Publication year： Oct. 01, 2009 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *bacterium ,...
Semi thesaurus term： carboxyl group ,...

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JST classification (2)： Enzyme in general  (EB09010D) ,  Microorganism biochemistry  (EG03020N)

Substance index (2)： Palmitoyl CoA ,  Pyridoxal Phosphate

Reference (46)：

• UCHIDA, Y. Omega-O-acylceramide, a lipid essential for mammalian survival. J. Dermatol. Sci. 2008, 51, 77-87
• FUTERMAN, A. H. The complex life of simple sphingolipids. EMBO Rep. 2004, 5, 777-782
• SPIEGEL, S. Sphingosine-1-phosphate : an enigmatic signalling lipid. Nat. Rev. Mol. Cell. Biol. 2003, 4, 397-407
• MUNRO, S. Lipid rafts : elusive or illusive?. Cell. 2003, 115, 377-388
• HANADA, K. Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. Biochim. Biophys. Acta. 2003, 1632, 16-30

Terms in the title (5)： Sphingobacterium ,  セリンパルミトイルトランスフェラーゼ ,  酵素 ,  メカニズム ,  洞察