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J-GLOBAL ID：200902223231055682   Reference number：07A1201156

Radical Scavenging Activity and Inhibition of Macrophage NO Production by Fukinolic Acid, a Main Phenolic Constituent in Japanese Butterbur (Petasites japonicus)

フキ(Petasites japonicus)の主なフェノール類成分であるフキノール酸によるラジカル捕捉活性及びマクロファージNO生成の阻害

Author (7)： WATANABE Satoru (Tokyo Seiei Coll., Tokyo, JPN) ,  HASHIMOTO Ken (Meikai Univ. School of Dentistry, Saitama, JPN) ,  TAZAKI Hiroyuki (Nippon Veterinary and Life Sci. Univ., Tokyo, JPN) ,  IWAMOTO Yuzuri (Osaka Prefectural Government, Osaka, JPN) ,  SHINOHARA Naoko (Tokyo Seiei Coll., Tokyo, JPN) ,  SATOH Kazue (Showa Univ., Tokyo, JPN) ,  SAKAGAMI Hiroshi (Meikai Univ. School of Dentistry, Saitama, JPN)
Material： Food Science and Technology Research  (Food Sci Technol Res)
Volume： 13  Issue： 4  Page： 366-371  Publication year： Nov. 2007 
JST Material Number： L2827A  ISSN： 1344-6606  CODEN： FSTRFS  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Petasites ,...
Semi thesaurus term： Petasites japonicus

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JST classification (2)： Plant biochemistry  (EH01050J) ,  Biological function  (EB02020R)

Substance index (5)： DPPH ,  (-)-Epigallocatechin gallate ,  Gallic Acid ,  Chlorogenic Acid ,  Fukinolic acid

Reference (16)：

• Burdette, J.E., Chen, S.N., Lu, Z.Z., Xu, H., White, B.E., Fabricant, D.S., Liu, J., Fong, H.S., Farnsworth, N.R., Constantinou, A.I., Van Breemen, R.V., Pezutto, J.M. and Bolton, J.L. (2002). Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species : bioassay-directed isolation and characterization of active principles. J. Agric. Food Chem., 50, 7022-7028.
• Endo, M. and Kuroiwa, Y. (2005). Neurotransmitter related to headache. J. Clin. Exp. Exp. Med. (Igaku no Ayumi) 215, 1071-1074 (in Japanese).
• Hasa, Y. and Tazaki, H. (2004). Biosynthesis of fukinolic acid, isolated from Petasites japonicus. Biosci. Biotechnol. Biochem., 68, 2212-2214.
• Iwamoto Y., Nakasone W. and Ezura H. (2007). Efficient selection of a high-yield line by using somaclonal variation in Japanese butterbur (Petasites japonicus). Plant Biotechnol. 24, 289-293.
• Islam, MD. S., Yoshimoto, M., Yahara, S., Okuno, S., Ishiguro, K. and Yamakawa, O. (2002). Identification and characterization of foliar polyphenolic composition in sweet potato (Ipomoea batatas L.) genotypes. J. Agric. Food. Chem., 50, 3718-3722.

Terms in the title (8)： フキ ,  Petasites ,  フェノール類 ,  フキノール酸 ,  ラジカル捕捉活性 ,  マクロファージ ,  NO ,  阻害