Art

J-GLOBAL ID：200902223467547071   Reference number：05A0496125

Biochemical and Molecular Pharmacological Aspects of Transporters as Determinants of Drug Disposition

薬物動態の決定因子としての輸送体の生化学的及び分子薬理学的特徴

Author (1)： SAI Yoshimichi (Kyoritsu Univ. Pharmacy, Tokyo, JPN)
Material： Drug Metabolism and Pharmacokinetics  (Drug Metab Pharmacokinet)
Volume： 20  Issue： 2  Page： 91-99  Publication year： Apr. 25, 2005 
JST Material Number： X0758A  ISSN： 1347-4367  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *pharmacokinetics ,...
Semi thesaurus term： SLCファミリー輸送体 ,...

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JST classification (2)： Transport of cell membrane  (EF04020R) ,  Basic biopharmacy  (GY01021U)

Reference (38)：

• 1) Sai, Y. and Tsuji, A.: Transporter-mediated drug delivery: recent progress and experimental approaches. Drug Discov. Today, 9: 712-720 (2004).
• 2) Fei, Y. J., Kanai, Y., Nussberger, S., Ganapathy, V., Leibach, F. H., Romero, M. F., Singh, S. K., Boron, W. F. and Hediger, M. A.: Expression cloning of a mammalian proton-coupled oligopeptide transporter. Nature, 368: 563-566 (1994).
• 3) Sekine, T., Watanabe, N., Hosoyamada, M., Kanai, Y. and Endou, H.: Expression cloning and characterization of a novel multispecific organic anion transporter. J. Biol. Chem., 272: 18526-1859 (1997).
• 4) Grundemann, D., Gorboulev, V., Gambaryan, S., Veyhl, M. and Koepsell, H.: Drug excretion mediated by a new prototype of polyspecific transporter. Nature, 372: 549-552 (1994).
• 5) Jacquemin, E., Hagenbuch, B., Stieger, B., Wolkoff, A. W. and Meier, P. J.: Expression cloning of a rat liver Na(+)-independent organic anion transporter. Proc. Natl. Acad. Sci. U.S.A., 91: 133-137 (1994).

Terms in the title (5)： 薬物動態 ,  決定因子 ,  輸送体 ,  生化学 ,  分子薬理学