Art

J-GLOBAL ID：200902223637525132   Reference number：09A0459988

Novel 3,4-Diazabenzotropone Compounds (2,3-Benzodiazepin-5-ones): Synthesis, Unique Reactivity, and Biological Evaluation

新しい3,4-ジアザベンゾトロポン化合物(2,3-ベンゾジアゼピン-5-オン類) 合成,ユニークな反応性,および生物学的評価

Author (6)： MATSUYA Yuji (Univ. Toyama, Toyama, JPN) ,  KATAYANAGI Hiroshi (Univ. Toyama, Toyama, JPN) ,  OHDAIRA Takuya (Univ. Toyama, Toyama, JPN) ,  WEI Zheng-Li (Univ. Toyama, Toyama, JPN) ,  KONDO Takashi (Univ. Toyama, Toyama, JPN) ,  NEMOTO Hideo (Univ. Toyama, Toyama, JPN)
Material： Organic Letters  (Org Lett)
Volume： 11  Issue： 6  Page： 1361-1364  Publication year： Mar. 19, 2009 
JST Material Number： W1171A  ISSN： 1523-7060  CODEN： ORLEF7  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： ring-opening reaction ,  cyclization reaction ,  *nitrogen heterocyclic compound ,  *polynuclear aromatic compound ,  aromatic ketone ,  chemical synthesis ,  denitrification reaction ,  addition reaction ,  *induction ,  antioxidant ,  U937 cell ,  *apoptosis induction ,  antioxidants ,  electrocyclic reaction ,  *Benzodiazepines
Semi thesaurus term： electrocyclization ,  *Benzodiazepines

JST classification (2)： Seven-membered heterocyclic compounds  (CF07110I) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (13)： 1-Phenyl-5-oxo-7,8-dimethoxy-5H-2,3-benzodiazepine-4-carboxylic acid ethyl ester ,  1-(4-Methylphenyl)-5-oxo-7,8-dimethoxy-5H-2,3-benzodiazepine-4-carboxylic acid ethyl ester ,  1-(2-Methylphenyl)-5-oxo-7,8-dimethoxy-5H-2,3-benzodiazepine-4-carboxylic acid ethyl ester ,  1-(4-Methoxyphenyl)-5-oxo-7,8-dimethoxy-5H-2,3-benzodiazepine-4-carboxylic acid ethyl ester ,  1-(4-Bromophenyl)-5-oxo-7,8-dimethoxy-5H-2,3-benzodiazepine-4-carboxylic acid ethyl ester ,  1-[4-(Trifluoromethyl)phenyl]-5-oxo-7,8-dimethoxy-5H-2,3-benzodiazepine-4-carboxylic acid ethyl ester ,  1-Oxo-3-phenyl-5,6-dimethoxy-1H-indene-2-carboxylic acid ethyl ester ,  3-(4-Methylphenyl)-1-oxo-5,6-dimethoxy-1H-indene-2-carboxylic acid ethyl ester ,  3-(2-Methylphenyl)-1-oxo-5,6-dimethoxy-1H-indene-2-carboxylic acid ethyl ester ,  3-(4-Methoxyphenyl)-1-oxo-5,6-dimethoxy-1H-indene-2-carboxylic acid ethyl ester ,  3-(4-Bromophenyl)-1-oxo-5,6-dimethoxy-1H-indene-2-carboxylic acid ethyl ester ,  3-[4-(Trifluoromethyl)phenyl]-1-oxo-5,6-dimethoxy-1H-indene-2-carboxylic acid ethyl ester ,  1-(Benzylamino)-1-phenyl-5-oxo-7,8-dimethoxy-4,5-dihydro-1H-2,3-benzodiazepine-4-carboxylic acid ethyl ester

Terms in the title (2)： 反応性 ,  生物学的評価