Art

J-GLOBAL ID：200902223750315888   Reference number：06A0694165

Change of Subgingival Bacterial Flora and Drug Concentration Level in Gingiva of Periodontal Patients Systemically Administered Azithromycin

アジスロマイシンの全身投与を受けた歯周炎患者の歯肉における歯肉内細菌叢と薬物濃度レベルの変化

Author (8)： GOMI Kazuhiro (Tsurumi Univ., Kanagawa) ,  SHIBUKAWA Naoya (Tsurumi Univ., Kanagawa) ,  YASHIMA Akihiro (Tsurumi Univ., Kanagawa) ,  IINO Fumiaki (Tsurumi Univ., Kanagawa) ,  KANAZASHI Mikimoto (Tsurumi Univ., Kanagawa) ,  OHSHIMA Tomoko (Tsurumi Univ., Kanagawa) ,  MAEDA Nobuko (Tsurumi Univ., Kanagawa) ,  ARAI Takashi (Tsurumi Univ., Kanagawa)
Material： Dentistry in Japan  (Dent Jpn)
Volume： 41  Page： 151-155  Publication year： Mar. 2005 
JST Material Number： L0818A  ISSN： 0070-3737  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *periodontitis ,...

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JST classification (1)： Drug therapy(=pharmacotherapy) for tooth and mouth(=oral cavity)  (GT05050X)

Substance index (1)： Azithromycin

Reference (8)：

• GREENBERG, R. N. Overview of patient compliance with medication dosing : a literature review. Clin. Ther. 1984, 6, 592-599
• WILLIAMS, J. D. Comparative in vitro activity of azithromycin, macrolides (erythromycin, clarithromycin and spiramycin) and streptogramin RP 59500 against oral organisms. J. Antimicrob. Chemother. 1992, 30, 27-37
• FOULDS, G. The paramacokinetics of azithromycin in human serum and tissue. J. Antimicrob. Chemother. 1990, 25, suppl A, 73-82
• GLADUE, R. P. In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells : possible mechanism of delivery and release at sites of infection. Antimicrob. Agents Chemother. 1989, 33, 277-282
• MCDONALD, P. J. Phagocytic uptake and transport of azithromycin. Eur. J. Clin. Microbiol. Infect. Dis. 1991, 10, 828-833

Terms in the title (7)： アジスロマイシン ,  全身投与 ,  歯周炎 ,  患者 ,  歯肉 ,  細菌叢 ,  薬物濃度