Art

J-GLOBAL ID：200902224980126886   Reference number：07A1012954

Potent Inhibition of HIV-1 Replication by Novel Non-peptidyl Small Molecule Inhibitors of Protease Dimerization

プロテアーゼの二量化の新規非ペプチジル低分子阻害剤によるHIV1複製の強力な阻害

Author (13)： KOH Yasuhiro (Kumamoto Univ. Graduate School of Medical and Pharmaceutical Sci., Kumamoto, JPN) ,  MATSUMI Shintaro (Kumamoto Univ. Graduate School of Medical and Pharmaceutical Sci., Kumamoto, JPN) ,  DAS Debananda (National Inst. Health, Maryland) ,  AMANO Masayuki (Kumamoto Univ. Graduate School of Medical and Pharmaceutical Sci., Kumamoto, JPN) ,  DAVIS David A. (National Inst. Health, Maryland) ,  LI Jianfeng (Purdue Univ., Indiana) ,  LESCHENKO Sofiya (Purdue Univ., Indiana) ,  BALDRIDGE Abigail (Purdue Univ., Indiana) ,  SHIODA Tatsuo (Osaka Univ., Osaka, JPN) ,  YARCHOAN Robert (National Inst. Health, Maryland) ,  GHOSH Arun K. (Purdue Univ., Indiana) ,  MITSUYA Hiroaki (Kumamoto Univ. Graduate School of Medical and Pharmaceutical Sci., Kumamoto, JPN) ,  MITSUYA Hiroaki (National Inst. Health, Maryland)
Material： Journal of Biological Chemistry  (J Biol Chem)
Volume： 282  Issue： 39  Page： 28709-28720  Publication year： Sep. 28, 2007 
JST Material Number： E0038A  ISSN： 0021-9258  CODEN： JBCHA3  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： proteinase inhibitor ,...
Semi thesaurus term： HIV protease inhibitor

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JST classification (1)： Basic research of antiviral drugs  (GW17040O)

Substance index (8)： Tipranavir ,  GRL-0036A ,  GRL-06579A ,  GRL-98065 ,  TMC-126 ,  Darunavir ,  VX-385 ,  GRL-0026A

Terms in the title (6)： プロテアーゼ ,  二量化 ,  低分子 ,  阻害剤 ,  HIV1複製 ,  阻害