Art

J-GLOBAL ID：200902225121672310   Reference number：04A0825862

Effects of Troglitazone on Diabetic Nephropathy and Hypercoagulation in KK and KK-A^y Mice Fed a High Fructose Diet

高フルクトース食摂取KKおよびKK-A^yマウスにおける糖尿病性ネフロパシーおよび凝固高進に対するトログリタゾンの作用

Author (7)： OKAZAKI M (Showa Univ. School of Medicine, Tokyo, JPN) ,  TAKINISHI Y (Showa Univ. School of Medicine, Tokyo, JPN) ,  TANAKA M (Showa Univ. School of Medicine, Tokyo, JPN) ,  ASANO Y (Showa Univ. School of Medicine, Tokyo, JPN) ,  GOMIBUCHI H (Showa Univ. School of Medicine, Tokyo, JPN) ,  TSUCHIYA S (Showa Univ. School of Medicine, Tokyo, JPN) ,  OGUCHI K (Showa Univ. School of Medicine, Tokyo, JPN)
Material： Showa University Journal of Medical Sciences  (Showa Univ J Med Sci)
Volume： 16  Issue： 2  Page： 109-116  Publication year： Jun. 2004 
JST Material Number： L1154A  ISSN： 0915-6380  CODEN： SUMSEG  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： *non-insulin-dependent diabetes mellitus ,...

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JST classification (1)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q)

Substance index (4)： Troglitazone ,  Glucose ,  Creatinine ,  Fructose

Reference (25)：

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• 3) Sievers MK, Bennett PH and Nelson RG : Effect of glycemia on mortality in Pima Indians with type 2 diabetes. Diabetes 48 : 896-902 (1999)
• 4) UK Prospective Diabetes Study Group : association of glucaemia with macrovascular and microvascular complication of type 2 diabetes (UKPDS 35) : prospective observational study. BMJ 321 : 405-412 (2000)
• 5) Oguchi M, Wada K, Honma H, Tanaka A, Kaneko T, Sakakibara S, Ohsumi J, Serizawa N, Fujiwara T, Horikoshi, H and Fujita T : Molecular design, synthesis and hypoglycemic activity of a series of thiazolidine-2, 4-diones. J Med Chem 43 : 3052-3066 (2000)

Terms in the title (5)： 高フルクトース食 ,  KK-Ayマウス ,  糖尿病性ネフロパシー ,  凝固高進 ,  トログリタゾン