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J-GLOBAL ID:200902225520890622   Reference number:08A0468683

Inhibition of the Outgrowth and Elongation of Neurites from Pheochromocytoma Cells by 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Preventive Effects of Dimethylsulfoniopropionate in the Presence of Nerve Growth Factor

褐色細胞腫細胞からの軸索突起の伸出及び伸長に対する1-メチル-4-フェニル-1,2,3,6-テトラヒドロピリジンによる阻害と神経成長因子存在下のジメチルスルホニオプロピオナートの予防効果
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Volume: 54  Issue:Page: 176-180  Publication year: Apr. 2008 
JST Material Number: F0733A  ISSN: 0301-4800  CODEN: JNSVA5  Document type: Article
Article type: 短報  Country of issue: Japan (JPN)  Language: ENGLISH (EN)
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Reference (30):
  • 1) Burns RS, Chiueh CC, Markey SP, Ebert M, Jacobowittz DM, Kopin IJ. 1983. A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA 80: 4546-4550.
  • 2) Riederer P, Gille G, Muller T, Przuntek H, Reichmann H, Riess O, Schwarz Vogt AT. 2002. Practical importance of neuroprotection in Parkinson's disease. J Neurol 249 (Suppl 3): III/53-III/56.
  • 3) Riederer P, Foley P, Bringmann G, Feneis D, Bruckner R, Gerlach M. 2002. Biochemical and pharmacological characterization of 1-trichloro-methyl-1,2,3,6-tetrahydro-β-carboline: a biologically relevant neurotoxin? Eur J Pharmacol 442: 1-16.
  • 4) Fuchs GA, Gemende I, Herting B, Lemke MR, Reichmann OH, Rieke J, Emmans D, Volkmann J. 2004. Dementia in idiopathic Parkinson's syndrome. J Neurol 251 (Suppl 6): VI/28-32.
  • 5) McNaught KS, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa C, Jenner P, Marsden CD. 1998. Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease. Biochem Pharmacol 56: 921-933.
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