Art

J-GLOBAL ID：200902226960386981   Reference number：06A0171191

Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates

免疫反応を抑制した非ヒト霊長類に野生型ブタすい島の門脈内異種移植を行うと糖尿病の長期間にわたる回復が見られる

Author (19)： HERING Bernhard J (Univ. Minnesota, Minnesota, USA) ,  WIJKSTROM Martin (Univ. Minnesota, Minnesota, USA) ,  GRAHAM Melanie L (Univ. Minnesota, Minnesota, USA) ,  HARDSTEDT Maria (Univ. Minnesota, Minnesota, USA) ,  AASHEIM Tor C (Univ. Minnesota, Minnesota, USA) ,  JIE Tun (Univ. Minnesota, Minnesota, USA) ,  ANSITE Jeffrey D (Univ. Minnesota, Minnesota, USA) ,  NAKANO Masahiko (Univ. Minnesota, Minnesota, USA) ,  CHENG Jane (Immerge BioTherapeutics, Inc., Massachusetts, USA) ,  LI Wei (Immerge BioTherapeutics, Inc., Massachusetts, USA) ,  MORAN Kathleen (Immerge BioTherapeutics, Inc., Massachusetts, USA) ,  CHRISTIANS Uwe (Univ. Colorado Health Sci. Center, Colorado, USA) ,  FINNEGAN Colleen (Univ. Minnesota, Minnesota, USA) ,  MILLS Charles D (Univ. Minnesota, Minnesota, USA) ,  SUTHERLAND David E (Univ. Minnesota, Minnesota, USA) ,  BANSAL-PAKALA Pratima (Univ. Minnesota, Minnesota, USA) ,  MURTAUGH Michael P (Univ. Minnesota, Minnesota, USA) ,  KIRCHHOF Nicole (Univ. Minnesota, Minnesota, USA) ,  SCHUURMAN Henk-Jan (Immerge BioTherapeutics, Inc., Massachusetts, USA)
Material： Nature Medicine  (Nat Med)
Volume： 12  Issue： 3  Page： 301-303  Publication year： Mar. 01, 2006 
JST Material Number： W0636A  ISSN： 1078-8956  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *heterotrans plantation ,...
Semi thesaurus term： bridged compound ,...

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JST classification (2)： Treatment for metabolic diseases,nutritional diseases.  (GD05030F) ,  Experimental treatment for tumors  (GE02040Y)

Substance index (4)： Fingolimod Hydrochloride ,  Tacrolimus ,  Leflunomide ,  Everolimus

Terms in the title (11)： 免疫反応 ,  ヒト ,  霊長類 ,  野生型 ,  ブタ ,  すい島 ,  門脈 ,  異種移植 ,  糖尿病 ,  長期間 ,  回復