Silent information regulator, Sirtuin 1, and age-related diseases

ZENG Li; CHEN Rui; CHEN Rui; LIANG Fengxia; LIANG Fengxia; TSUCHIYA Hiroshi; MURAI Hiroshi; NAKAHASHI Takeshi; IWAI Kunimitsu; TAKAHASHI Takashi; TAKAHASHI Takashi; KANDA Tsugiyasu; MORIMOTO Shigeto

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J-GLOBAL ID：200902227637679925 Reference number：09A0427622

Silent information regulator, Sirtuin 1, and age-related diseases

サイレント情報制御因子,シルツイン1,と年齢に関連した疾病

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Volume： 9 Issue： 1 Page： 7-15 Publication year： Mar. 2009
JST Material Number： W1574A ISSN： 1444-1586 Document type： Article
Article type：文献レビュー Country of issue： United States (USA) Language： ENGLISH (EN)

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Enzyme in general

Reference (75)：

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IMAI, S. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature. 2000, 403, 795-800
JEONG, J. SIRT1 promotes DNA repair activity and deacetylation of Ku70. Exp Mol Med. 2007, 39, 8-13
COHEN, HY. Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell. 2004, 13, 627-638
NARALA, SR. SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity. Mol Biol Cell. 2008, 19, 1210-1219

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