Random Mutagenesis of the M<sub>3</sub> Muscarinic Acetylcholine Receptor Expressed in Yeast  IDENTIFICATION OF POINT MUTATIONS THAT “SILENCE” A CONSTITUTIVELY ACTIVE MUTANT M<sub>3</sub> RECEPTOR AND GREATLY IMPAIR RECEPTOR/G PROTEIN COUPLING.

SCHMIDT C; LI B; BLOODWORTH L; ERLENBACH I; ZENG F-Y; WESS J

Art

J-GLOBAL ID：200902227749614605 Reference number：03A0591632

Random Mutagenesis of the M₃ Muscarinic Acetylcholine Receptor Expressed in Yeast IDENTIFICATION OF POINT MUTATIONS THAT “SILENCE” A CONSTITUTIVELY ACTIVE MUTANT M₃ RECEPTOR AND GREATLY IMPAIR RECEPTOR/G PROTEIN COUPLING.

酵母で発現したM₃ムスカリン性アセチルコリン受容体の無作為突然変異構成的活性変異体M₃受容体を沈黙させ,受容体/G蛋白質共役を甚だしく障害する点突然変異の同定

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Material：
Volume： 278 Issue： 32 Page： 30248-30260 Publication year： Aug. 08, 2003
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Biological function , Cell physiology in general

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Random Mutagenesis of the M3 Muscarinic Acetylcholine Receptor Expressed in Yeast IDENTIFICATION OF POINT MUTATIONS THAT “SILENCE” A CONSTITUTIVELY ACTIVE MUTANT M3 RECEPTOR AND GREATLY IMPAIR RECEPTOR/G PROTEIN COUPLING.

Random Mutagenesis of the M₃ Muscarinic Acetylcholine Receptor Expressed in Yeast IDENTIFICATION OF POINT MUTATIONS THAT “SILENCE” A CONSTITUTIVELY ACTIVE MUTANT M₃ RECEPTOR AND GREATLY IMPAIR RECEPTOR/G PROTEIN COUPLING.