Art

J-GLOBAL ID：200902227775132058   Reference number：05A0703733

Results of clinical trial of intravenous rt-PA (alteplase) for acute ischemic stroke

線溶療法 発症3時間以内の虚血性脳血管障害に対するGMK-527(アルテプラーゼ)静注療法臨床試験の結果

Author (7)： MINEMATSU KAZUO (国立循環器病セ) ,  YAMAGUCHI TAKENORI (国立循環器病セ) ,  HASHI KAZUO (太平洋脳神経外科コンサルティング) ,  SHINOHARA YUKITO (東海大) ,  SAITO ISAMU (富士脳障害研) ,  MORI ETSURO (東北大 大学院) ,  NAKAGAWARA JOJI (中村記念病院)
Material： 脳卒中  (日本脳卒中学会機関誌)
Volume： 26  Issue： 4  Page： 603-606  Publication year： Dec. 25, 2004 
JST Material Number： X0160A  ISSN： 0912-0726  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human ,...
Semi thesaurus term： acute phase

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JST classification (2)： Drug therapy(=pharmacotherapy)for nervous system diseases  (GN05020Y) ,  Clinical application of enzyme preparations and inhibitor preparations  (GW21020H)

Reference (6)：

• The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995, 333, 1581-1587
• KIMURA, K. Analysis of 16,922 patients with acute ischemic stroke and transient ischemic attack in Japan. Cerebrovasc Dis. 2004, 18, 47-56
• ADAMS, HP Jr. Guidelines for thrombolytic therapy for acute stroke : A supplement to the guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke. 1996, 27, 1711-1718
• UESHIMA, S. The differences in thrombolytic effects of administrated recombinant t-PA between Japanese and Caucasians. Thromb Haemost. 2002, 87, 544-546
• YAMAGUCHI, T. Clinical efficacy and safety of intravenous tissue plasminogen activator in acute embolic stroke : A randomized, double-blind, dose-comparison study of duteplase. Thrombolytic therapy in acute ischemic stroke. 1995, III, 223-229

Terms in the title (7)： 線溶療法 ,  発症 ,  虚血性脳血管障害 ,  アルテプラーゼ ,  静注 ,  療法 ,  臨床試験