Art

J-GLOBAL ID：200902227998446062   Reference number：08A0626201

Protective effect of nasal immunization of influenza virus hemagglutinin with recombinant cholera toxin B subunit as a mucosal adjuvant in mice

マウスにおいて組換コレラ毒素Bサブユニットを粘膜アジュバントとして用いたインフルエンザウイルス血球凝集素の鼻内免疫の保護作用

Author (14)： ISAKA Masanori (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  ZHAO Yanqiu (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  ZHAO Yanqiu (Jilin Univ., Changchun, CHN) ,  NOBUSAWA Eri (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  NAKAJIMA Setsuko (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  NAKAJIMA Katsuhisa (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  YASUDA Yoko (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  YASUDA Yoko (Kinjo Gakuin Univ., Nagoya, JPN) ,  MATSUI Hideyuki (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  HASEGAWA Tadao (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN) ,  MAEYAMA Jun-ichi (National Inst. Infectious Diseases, Tokyo, JPN) ,  MOROKUMA Kazunori (Chemo-Sero-Therapeutic Res. Inst., Kumamoto, JPN) ,  OHKUMA Kunio (Chemo-Sero-Therapeutic Res. Inst., Kumamoto, JPN) ,  TOCHIKUBO Kunio (Nagoya City Univ. Graduate School of Medical Sci., Aichi, JPN)
Material： Microbiology and Immunology  (Microbiol Immunol)
Volume： 52  Issue： 2  Page： 55-63  Publication year： Feb. 2008 
JST Material Number： W1957A  ISSN： 0385-5600  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *adjuvant ,...
Semi thesaurus term： Influenzavirus A ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=08A0626201&from=J-GLOBAL&jstjournalNo=W1957A") }}

JST classification (2)： Infectious immunity  (ED03030P) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Reference (34)：

• CLEMENTS, J. D. Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine. 1988, 6, 269-277
• DEHAAN, L. Mutational analysis of the role of ADP-ribosylation activity and GM1-binding activity in the adjuvant properties of the Escherichia coli heat-labile enterotoxin towards intranasally administered keyhole limpet hemocyanin. Eur J Immunol. 1998, 28, 1243-1250
• ELSON, C. O. Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen. J Immunol. 1984, 133, 2892-2897
• LYCKE, N. Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology. 1986, 59, 301-308
• TAMURA, S. Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit. Vaccine. 1988, 6, 409-413

Terms in the title (9)： マウス ,  組換 ,  コレラ毒素Bサブユニット ,  粘膜アジュバント ,  インフルエンザ ,  ウイルス血球凝集素 ,  鼻 ,  免疫 ,  保護作用