Art

J-GLOBAL ID：200902229052055449   Reference number：03A0271739

Inhibitory Effect of Azelastine on Allergic Itch-Associated Response in Mice Sensitized With Mosquito Salivary Glands Extract

カ唾液腺抽出物で感作したマウスのアレルギー性そうよう関連反応に対するアゼラスチンの阻害効果

Author (6)： OHTSUKA E (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  KAWAI S (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  NOJIMA H (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  ANDOH T (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  KAMIMURA K (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  KURAISHI Y (Toyama Medical and Pharmaceutical Univ., Toyama, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 91  Issue： 3  Page： 263-266  Publication year： Mar. 01, 2003 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Culicidae ,...
Semi thesaurus term： カアレルギー ,...

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JST classification (1)： Basic research of histaminergic drugs and antihistaminergic drugs  (GW06010V)

Substance index (3)： Azelastine ,  Terfenadine ,  Dexamethasone

Reference (15)：

• 1 Ohtsuka E, Kawai S, Ichikawa T, Nojima H, Kitagawa K, Shirai Y, Kamimura K and Kuraishi Y: Roles of mast cells and histamine in mosquito bite-induced allergic itch-associated responses in mice. Jpn J Pharmacol 86, 97 – 105 (2001)
• 2 Chand N and Sofia RD: Azelastine – a novel in vivo inhibitor of leukotriene biosynthesis: a possible mechanism of action: a mini review. J Asthma 32, 227 – 234 (1995)
• 3 Endo K, Sano H, Fukuzumi T, Adachi J and Aoki T: Objective scratch monitor evaluation of the effect of an antihistamine on nocturnal scratching in atopic dermatitis. J Dermatol Sci 22, 54 – 61 (1999)
• 4 Kanai H, Nagashima A, Hirakata E, Hirakata H, Okuda S, Fujimi S and Fujishima M: The effect of azelastin hydrochloride on pruritus and leukotriene B₄ in hemodialysis patients. Life Sci 57, 207 – 213 (1995)
• 5 Andoh T and Kuraishi Y: Inhibitory effects of azelastine on substance P-induced itch-associated response in mice. Eur J Pharmacol 436, 235 – 239 (2002)

Terms in the title (7)： 唾液腺 ,  抽出物 ,  感作 ,  マウス ,  そうよう ,  アゼラスチン ,  阻害効果