Art

J-GLOBAL ID：200902231802153264   Reference number：06A0848274

Antimalarial Activity of Crambescidin 800 and Synthetic Analogues against Liver and Blood Stage of Plasmodium sp.

肝臓および血液ステージPlasmodium sp.に対するクランベシジン800と合成類似体の抗マラリア活性

Author (14)： LAZARO J. Enrico H. (Univ. Philippines, Quezon City, PHL) ,  NITCHEU Josiane (Univ. Pierre et Marie Curie, Paris, FRA) ,  MAHMOUDI Nassira (Univ. Pierre et Marie Curie, Paris, FRA) ,  IBANA Joyce A. (Univ. Philippines, Quezon City, PHL) ,  MANGALINDAN Gina C. (Univ. Philippines, Quezon City, PHL) ,  BLACK Gregory P. (Univ. Wales, Gwynedd, GBR) ,  HOWARD-JONES Andrew G. (Univ. Wales, Gwynedd, GBR) ,  MOORE Christopher G. (Univ. Wales, Gwynedd, GBR) ,  THOMAS Dafydd A. (Univ. Wales, Gwynedd, GBR) ,  MAZIER Dominique (Univ. Pierre et Marie Curie, Paris, FRA) ,  IRELAND Chris M. (Univ. Utah, UT, USA) ,  CONCEPCION Gisela P. (Univ. Philippines, Quezon City, PHL) ,  MURPHY Patrick J. ,  DIQUET Bertrand (Univ. Pierre et Marie Curie, Paris, FRA)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 59  Issue： 9  Page： 583-590  Publication year： Sep. 25, 2006 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...

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JST classification (2)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C) ,  Synthesis of antibiotics  (GX04000Z)

Substance index (3)： Crambescidin 800 ,  Ptilomycalin A ,  N-(4-Aminobutyl)-N-(3-aminopropyl)-12-[[(2S)-2α,2:5α,5-bis(epoxybutano)-1,3,5,6,6aα,10bα-hexahydro-2H-3,4,10c-triazafluoranthene-8-yl]methoxy]lauric amide

Reference (22)：

• JARES-ERIJMAN, EA. Crambescidins : new antiviral and cytotoxic compounds from the sponge Crambe crambe. J Org Chem. 1991, 56, 5712-5715
• BLACK, GP. Synthesis and biological activity of analogues of ptilomycalin A. Tetrahedron Lett. 2001, 42, 3377-3381
• BLACK, GP. Synthesis of the left hand unit of batzelladine F : revision of the reported relative stereochemistry. Tetrahedron. 1999, 55, 6547-6554
• CAUKETT, P. Synthesis of a novel C2 symmetric guanidine base. J Org Chem. 1999, 64, 1039-1041
• BLACK, GP. A short synthetic route to the tricyclic guanidinium core of the batzelladine alkaloids. Tetrahedron. 1998, 54, 9481-9488

Terms in the title (7)： 肝臓 ,  血液 ,  ステージ ,  Plasmodium ,  クランベシジン800 ,  類似体 ,  抗マラリア活性