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J-GLOBAL ID：200902232215038688   Reference number：05A0522304

INVOLVEMENT OF ACTIVATION OF NADPH OXIDASE AND EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) IN RENAL CELL INJURY INDUCED BY ZINC

亜鉛により誘導された腎細胞傷害におけるNADPHオキシダーゼおよび細胞外シグナル調節キナーゼ(ERK)の活性化の関与

Author (4)： MATSUNAGA YOSHIKO (Div. Of Pharmacology, Osaka Univ. Of Pharmaceutical Sciences) ,  KAWAI YOSHIKO (Div. Of Pharmacology, Osaka Univ. Of Pharmaceutical Sciences) ,  KOHDA YUKA (Div. Of Pharmacology, Osaka Univ. Of Pharmaceutical Sciences) ,  GEMBA MUNEKAZU (Div. Of Pharmacology, Osaka Univ. Of Pharmaceutical Sciences)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 30  Issue： 2  Page： 135-144 (J-STAGE)  Publication year： 2005
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *zinc ,...
Semi thesaurus term： NADH oxidoreductase ,...

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JST classification (4)： Toxicity of metals and metal compounds  (GZ02022V) ,  Cell physiology in general  (EF02010S) ,  Enzyme physiology  (EJ02020P) ,  Influence on plants  (EE05030G)

Substance index (3)： N,N'-Diphenyl-1,4-phenylenediamine ,  Diphenylene iodonium ,  U-0126

Reference (34)：

• Berg, J.M. and Shi, Y. (1996): The galvanization of biology: A growing appreciation for the roles of zinc. Science, 271, 1081-1085.
• Brenner, A.J. and Harris, E.D. (1995):A quantitative test for copper using bicinchoninic acid. Anal. Biochem., 226, 80-84.
• Celis, J.E. and Gromov, P. (2000): High-resolution two-dimensional gel electrophoresis and protein indentification using western blotting and ECL detection. EXS., 88, 55-67.
• Choi, D.W. and Koh, J.Y. (1998): Zinc and brain injury. Annu. Rev. Neurosci., 21, 347-375.
• Cui, X.L. and Douglas, J.G. (1997): Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells. Proc. Natl. Acad. Sci. U.S.A., 94, 3771-3776.

Terms in the title (8)： 亜鉛 ,  誘導 ,  腎細胞 ,  傷害 ,  NADPHオキシダーゼ ,  細胞外シグナル調節キナーゼ ,  ERK ,  活性化