Art

J-GLOBAL ID：200902233564954620   Reference number：03A0849953

Preparation of Deuterated Methyl and Dimethyl Substituted Nicotinoylating Agents for Derivatization of the N-Terminal of Protein

蛋白質のN末端の誘導体化のための重水素化メチル及びジメチル置換ニコチノイル化剤の合成

Author (5)： TSUMOTO H (Nagoya City Univ., Nagoya, JPN) ,  MURATA C (Nagoya City Univ., Nagoya, JPN) ,  MIYATA N (Nagoya City Univ., Nagoya, JPN) ,  TAGUCHI R (Nagoya City Univ., Nagoya, JPN) ,  KOHDA K (Nagoya City Univ., Nagoya, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 51  Issue： 12  Page： 1399-1401  Publication year： Dec. 01, 2003 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,...
Semi thesaurus term： N terminal ,...

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JST classification (2)： Pyridines  (CF07095Q) ,  Labeled compounds  (CB10050N)

Substance index (18)： Nicotinic acid ,  6-Methylnicotinic acid ,  6-(²H₃)Methylnicotinic acid ,  2-Methylnicotinic acid ,  2,6-Dimethylnicotinic acid ,  2,6-Bis[(²H₃)methyl]nicotinic acid ,  N-Hydroxysuccinimide ,  3-Pyridinecarboxylic acid succinimidyl ester ,  6-Methylnicotinic acid succinimidyl ester ,  6-(²H₃)Methylnicotinic acid succinimidyl ester ,  2-Methylnicotinic acid succinimidyl ester ,  2,6-Dimethylnicotinic acid succinimidyl ester ,  2,6-Bis[(²H₃)methyl]nicotinic acid succinimidyl ester ,  1-Methyl-3-(succinimidyloxycarbonyl)pyridinium ,  5-Bromonicotinic acid succinimidyl ester ,  6-Chloronicotinic acid succinimidyl ester ,  Isonicotinic acid succinimidyl ester ,  2-Pyridinecarboxylic acid succinimidyl ester

Reference (7)：

• 1) Gygi S. P., Rist B., Gerber S. A., Turecek F., Gelb M. H., Aebersold R., Nat. Biotechnol., 17, 994—999 (1999).
• 2) Münchback M., Quadroni M., Miotto G., James P., Anal. Chem., 72, 4047—4057 (2000).
• 3) Miyagi M., Nakao M., Nakazawa T., Kato I., Tsunasawa S., Rapid Commun. Mass Sp., 12, 603—608 (1998).
• 4) Guo W., Hinkle G. H., Lee R. J., J. Nucl. Med., 40, 1563—1569 (1999).
• 5) Christensen J. B., Molecules, 6, 47—51 (2001). [Online computer file.]

Terms in the title (6)： 蛋白質 ,  N末端 ,  誘導体化 ,  重水素化 ,  ジメチル ,  置換