Art

J-GLOBAL ID：200902234262848593   Reference number：07A0863890

Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice

エキソヌクレアーゼ-1欠損はDNA損傷情報伝達を損ない,テロメア不全マウスの寿命を延長させる

Author (15)： SCHAETZLEIN Sonja (Dep. of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, 30625 Hanover, DEU) ,  KODANDARAMIREDDY N.r. (Dep. of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, 30625 Hanover, DEU) ,  JU Zhenyu (Dep. of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, 30625 Hanover, DEU) ,  LECHEL Andre (Dep. of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, 30625 Hanover, DEU) ,  STEPCZYNSKA Anna (Dep. of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, 30625 Hanover, DEU) ,  LILLI Dana R. (Dep. of Cancer Biology, Abramson Family Cancer Res. Inst., Univ. of Pennsylvania School of Medicine, Philadelphia ...) ,  CLARK Alan B. (Lab. of Structural Biology, National Inst. of Environmental Health Sciences, Res. Triangle Park, NC 27709, USA) ,  RUDOLPH Cornelia (Inst. of Cell and Molecular Pathology, Medical School Hannover, 30625 Hannover, DEU) ,  WEI Kaichun (Dep. of Cell Biology, Albert Einstein Coll. of Medicine, Bronx, NY 10461, USA) ,  SCHLEGELBERGER Brigitte (Inst. of Cell and Molecular Pathology, Medical School Hannover, 30625 Hannover, DEU) ,  SCHIRMACHER Peter (Inst. of Pathology, Univ. Hospital, Im Neuenheimer Feld 220/221, 69120 Heidelberg, DEU) ,  KUNKEL Thomas A. (Lab. of Structural Biology, National Inst. of Environmental Health Sciences, Res. Triangle Park, NC 27709, USA) ,  GREENBERG Roger A. (Dep. of Cancer Biology, Abramson Family Cancer Res. Inst., Univ. of Pennsylvania School of Medicine, Philadelphia ...) ,  EDELMANN Winfried (Dep. of Cell Biology, Albert Einstein Coll. of Medicine, Bronx, NY 10461, USA) ,  RUDOLPH K. Lenhard (Dep. of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, 30625 Hanover, DEU)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 130  Issue： 5  Page： 863-877  Publication year： Sep. 07, 2007 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *exonuclease ,...
Semi thesaurus term： *cellular signal transduction ,...

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JST classification (2)： Enzyme in general  (EB09010D) ,  Aging and death  (EJ16040S)

Terms in the title (7)： エキソヌクレアーゼ ,  欠損 ,  DNA損傷 ,  情報伝達 ,  テロメア ,  マウス ,  寿命