Art

J-GLOBAL ID：200902234348036869   Reference number：09A0801388

Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer

乳癌におけるBIG3のPHB2/REA核輸送抑制作用を介したエストロジェン/エストロジェン受容体情報伝達の活性化

Author (12)： KIM Jung-Won (Univ. Tokyo, Tokyo, JPN) ,  AKIYAMA Miki (Univ. Tokyo, Tokyo, JPN) ,  PARK Jae-Hyun (Univ. Tokyo, Tokyo, JPN) ,  LIN Meng-Lay (Univ. Tokyo, Tokyo, JPN) ,  SHIMO Arata (Univ. Tokyo, Tokyo, JPN) ,  UEKI Tomomi (Univ. Tokyo, Tokyo, JPN) ,  DAIGO Yataro (Univ. Tokyo, Tokyo, JPN) ,  TSUNODA Tatsuhiko (RIKEN, Yokohama, JPN) ,  NISHIDATE Toshihiko (Univ. Tokyo, Tokyo, JPN) ,  NAKAMURA Yusuke (Univ. Tokyo, Tokyo, JPN) ,  KATAGIRI Toyomasa (Univ. Tokyo, Tokyo, JPN) ,  KATAGIRI Toyomasa (Univ. Tokushima, Tokushima, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 100  Issue： 8  Page： 1468-1478  Publication year： Aug. 2009 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *breast tumor ,...
Semi thesaurus term： *BIG3 ,...

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JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (2)： Guanine ,  Estradiol

Reference (30)：

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• YAGER, JD. Estrogen carcinogenesis in breast cancer. N Engl J Med. 2006, 354, 270-282
• BERRY, DA. Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med. 2005, 353, 1784-1792
• PETRICOIN, EF 3rd. Medical applications of microarray technologies : a regulatory science perspective. Nat Genet. 2002, 32, Suppl, 474-479

Terms in the title (9)： 乳癌 ,  BIG3 ,  PHB2 ,  核輸送 ,  抑制作用 ,  エストロジェン ,  エストロジェン受容体 ,  情報伝達 ,  活性化