Art

J-GLOBAL ID：200902235535413915   Reference number：09A0499890

Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial

進行胃癌患者における第一選択療法としてのカペシタビン/シスプラチンと5-フルオロウラシル/シスプラチンとの比較 無作為化第III相非劣性試験

Author (15)： KANG Y.-K. (Asan Medical Center) ,  KANG W.-K. (Samsung Medical Centre, Seoul, CHN) ,  SHIN D.-B. (Gil Medical Center, Incheon, KOR) ,  CHEN J. (Jiangsu Cancer Hospital, Jiangsu, CHN) ,  XIONG J. (Jiangxi Medical Coll., Jiangxi) ,  WANG J. (Shanghai Changzheng Hospital, Shanghai, CHN) ,  LICHINITSER M. (Russian Cancer Res. Center, Moscow, RUS) ,  GUAN Z. (Sun Yat-Sen Univ. Medical Sci., Guangzhou, CHN) ,  KHASANOV R. (Republic Oncology Hospital, Kazan, RUS) ,  ZHENG L. (Shanghai Xinhua Hospital, Shanghai, CHN) ,  PHILCO-SALAS M. (Hospital Sabogal, Lima, PER) ,  SUAREZ T. (Centro Medico Pensiones, Yucatan, MEX) ,  SANTAMARIA J. (Instituto Oncologico Nacional, Ancon, AUS) ,  FORSTER G. (Roche Pharmaceuticals, Taipei, CHN) ,  MCCLOUD P. I. (Roche Products Pty Ltd, Sydney, AUS)
Material： Annals of Oncology  (Ann Oncol)
Volume： 20  Issue： 4  Page： 666-673  Publication year： Apr. 2009 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *Progressive gastric carcinoma

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JST classification (2)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (2)： Fluorouracil ,  Capecitabine

Reference (18)：

• Pisters PWT, Kelsen DP, Tepper JE. Cancer of the stomach. In DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology, 8th edition. Philadelphia, PA: Wolters Kluwer Health and Lippincott Williams & Wilkins 2008; 1043-79.
• Kim N, Park YS, Heo DS et al. A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer. Cancer 1993;71: 3813-3818.
• Ohtsu A, Shimada Y, Shirao K et al. Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer: The Japan Clinical Oncology Group Study (JCOG9205). J Clin Oncol 2003; 21:54-59.
• Vanhoefer U, Rougier P, Wilke H et al. Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group. J Clin Oncol 2000; 18: 2648-2657.
• Wagner AD, Grothe W, Haerting J et al. Combination chemotherapies in advanced gastric cancer: an updated systematic review and meta-analysis. J Clin Oncol 2007; 25: 18S (Abstr 4555).

Terms in the title (7)： 進行胃癌 ,  患者 ,  第一選択療法 ,  カペシタビン ,  シスプラチン ,  5-フルオロウラシル ,  非劣性試験